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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2H
All Species:
22.42
Human Site:
Y93
Identified Species:
37.95
UniProt:
P52434
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52434
NP_006223.2
150
17143
Y93
D
Q
F
E
Y
V
M
Y
G
K
V
Y
R
I
E
Chimpanzee
Pan troglodytes
XP_526411
122
13830
D72
Y
E
D
G
T
L
D
D
G
E
Y
N
P
T
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
XP_996451
150
17237
Y93
D
Q
F
E
Y
V
M
Y
G
K
V
Y
R
I
E
Rat
Rattus norvegicus
XP_226176
151
17092
Y94
D
Q
F
E
Y
V
M
Y
G
K
V
Y
R
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232695
122
13865
E72
Y
G
K
V
Y
R
I
E
G
D
E
T
S
T
E
Frog
Xenopus laevis
NP_001085470
150
17139
Y93
D
Q
F
E
Y
I
M
Y
G
K
V
Y
R
I
E
Zebra Danio
Brachydanio rerio
NP_001017600
150
17108
Y93
D
Q
F
D
Y
V
M
Y
G
K
V
Y
R
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649352
149
17185
Y93
D
S
F
E
Y
V
M
Y
G
K
I
Y
R
I
E
Honey Bee
Apis mellifera
XP_394557
151
17160
M93
A
D
S
F
E
Y
V
M
S
G
M
V
Y
R
I
Nematode Worm
Caenorhab. elegans
Q19826
148
16993
G93
Q
Y
E
Y
V
M
Y
G
K
V
Y
R
L
E
D
Sea Urchin
Strong. purpuratus
XP_796332
151
17165
M93
A
D
S
F
E
Y
V
M
F
G
K
V
Y
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001147399
146
16550
G93
N
Y
E
Y
V
M
Q
G
K
L
Y
K
I
S
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_175827
146
16493
G95
K
Y
E
Y
I
M
H
G
K
L
Y
K
I
S
E
Baker's Yeast
Sacchar. cerevisiae
P20436
146
16493
D92
G
D
R
S
L
A
D
D
Y
D
Y
V
M
Y
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.3
N.A.
N.A.
N.A.
96.6
91.3
N.A.
N.A.
81.3
97.3
97.3
N.A.
78
77.4
63.3
82.7
Protein Similarity:
100
81.3
N.A.
N.A.
N.A.
98
94.6
N.A.
N.A.
81.3
100
98.6
N.A.
88.6
87.4
80.6
90.7
P-Site Identity:
100
6.6
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
20
93.3
93.3
N.A.
86.6
0
0
0
P-Site Similarity:
100
33.3
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
26.6
100
100
N.A.
93.3
13.3
13.3
6.6
Percent
Protein Identity:
N.A.
46.6
N.A.
48
36.6
N.A.
Protein Similarity:
N.A.
64.6
N.A.
68.6
58.6
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
20
N.A.
13.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
43
22
8
8
0
0
15
15
0
15
0
0
0
0
15
% D
% Glu:
0
8
22
36
15
0
0
8
0
8
8
0
0
8
65
% E
% Phe:
0
0
43
15
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
8
8
0
8
0
0
0
22
58
15
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
8
0
0
0
8
0
15
43
15
% I
% Lys:
8
0
8
0
0
0
0
0
22
43
8
15
0
0
0
% K
% Leu:
0
0
0
0
8
8
0
0
0
15
0
0
8
0
0
% L
% Met:
0
0
0
0
0
22
43
15
0
0
8
0
8
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
8
36
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
8
0
0
0
0
0
8
43
15
0
% R
% Ser:
0
8
15
8
0
0
0
0
8
0
0
0
8
15
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
0
8
0
15
0
% T
% Val:
0
0
0
8
15
36
15
0
0
8
36
22
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
22
0
22
50
15
8
43
8
0
36
43
15
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _