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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2J
All Species:
35.76
Human Site:
S99
Identified Species:
60.51
UniProt:
P52435
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52435
NP_006225.1
117
13293
S99
T
D
L
I
S
E
L
S
L
L
E
E
R
F
R
Chimpanzee
Pan troglodytes
XP_001135267
398
41732
S338
A
D
L
I
S
E
L
S
L
L
E
E
R
F
R
Rhesus Macaque
Macaca mulatta
XP_001114618
191
20609
S173
T
D
L
I
S
E
L
S
L
L
E
E
R
F
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O08740
117
13233
S99
T
D
L
I
S
E
L
S
L
L
E
E
R
F
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514119
117
13370
S99
T
D
L
I
S
E
L
S
L
L
E
E
R
F
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5XK67
114
13106
S101
V
L
N
T
F
E
T
S
I
K
E
Y
K
E
Q
Zebra Danio
Brachydanio rerio
Q6DRI4
112
12737
K105
E
A
R
M
K
E
F
K
E
Q
E
E
S
M
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJE4
117
13367
S99
T
D
L
L
A
E
L
S
L
F
E
E
R
F
K
Honey Bee
Apis mellifera
XP_624001
117
13510
S99
T
D
L
I
A
E
L
S
L
F
E
E
R
F
K
Nematode Worm
Caenorhab. elegans
Q9XVH6
122
13678
S98
T
D
L
V
G
E
L
S
L
L
E
H
R
I
D
Sea Urchin
Strong. purpuratus
XP_001197448
117
13241
S99
T
D
L
I
S
E
I
S
L
L
E
E
R
F
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142057
120
14102
E99
N
D
L
D
K
E
L
E
Y
L
K
Q
A
F
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38859
116
13545
D99
N
D
L
D
K
E
L
D
Y
L
K
N
Q
F
E
Baker's Yeast
Sacchar. cerevisiae
P38902
120
13597
G99
N
S
I
I
N
K
L
G
A
L
K
T
N
F
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.6
61.2
N.A.
N.A.
99.1
N.A.
N.A.
97.4
N.A.
31.6
30.7
N.A.
76.9
76
65.5
79.4
Protein Similarity:
100
27.6
61.2
N.A.
N.A.
99.1
N.A.
N.A.
97.4
N.A.
52.1
47.8
N.A.
88
90.5
76.2
90.6
P-Site Identity:
100
93.3
100
N.A.
N.A.
100
N.A.
N.A.
100
N.A.
20
20
N.A.
73.3
80
66.6
86.6
P-Site Similarity:
100
93.3
100
N.A.
N.A.
100
N.A.
N.A.
100
N.A.
40
26.6
N.A.
93.3
93.3
73.3
93.3
Percent
Protein Identity:
N.A.
49.1
N.A.
46.1
45.8
N.A.
Protein Similarity:
N.A.
71.6
N.A.
67.5
62.5
N.A.
P-Site Identity:
N.A.
40
N.A.
40
26.6
N.A.
P-Site Similarity:
N.A.
53.3
N.A.
53.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
15
0
0
0
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
79
0
15
0
0
0
8
0
0
0
0
0
0
8
% D
% Glu:
8
0
0
0
0
93
0
8
8
0
79
65
0
8
22
% E
% Phe:
0
0
0
0
8
0
8
0
0
15
0
0
0
79
0
% F
% Gly:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
8
58
0
0
8
0
8
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
22
8
0
8
0
8
22
0
8
0
15
% K
% Leu:
0
8
79
8
0
0
79
0
65
72
0
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
22
0
8
0
8
0
0
0
0
0
0
8
8
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
8
8
0
8
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
65
0
36
% R
% Ser:
0
8
0
0
43
0
0
72
0
0
0
0
8
0
0
% S
% Thr:
58
0
0
8
0
0
8
0
0
0
0
8
0
0
8
% T
% Val:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
15
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _