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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2J
All Species:
31.82
Human Site:
T20
Identified Species:
53.85
UniProt:
P52435
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52435
NP_006225.1
117
13293
T20
F
E
G
E
K
K
I
T
I
N
K
D
T
K
V
Chimpanzee
Pan troglodytes
XP_001135267
398
41732
S259
F
E
G
E
K
K
I
S
I
N
K
D
F
K
V
Rhesus Macaque
Macaca mulatta
XP_001114618
191
20609
T94
F
E
G
E
K
K
I
T
I
N
K
D
T
K
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O08740
117
13233
T20
F
E
G
E
K
K
I
T
I
N
K
D
T
K
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514119
117
13370
T20
F
E
G
E
K
K
I
T
I
N
K
D
T
K
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5XK67
114
13106
E21
V
Q
A
Q
G
N
E
E
S
C
V
T
F
V
L
Zebra Danio
Brachydanio rerio
Q6DRI4
112
12737
V26
D
E
G
C
V
T
F
V
L
N
E
E
D
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJE4
117
13367
I20
Y
E
G
E
K
K
I
I
K
E
L
D
T
K
V
Honey Bee
Apis mellifera
XP_624001
117
13510
I20
Y
E
G
E
K
K
I
I
K
E
Q
D
T
K
V
Nematode Worm
Caenorhab. elegans
Q9XVH6
122
13678
Y19
L
L
D
D
K
K
F
Y
I
E
K
D
T
K
V
Sea Urchin
Strong. purpuratus
XP_001197448
117
13241
T20
F
D
G
E
K
K
I
T
I
E
K
D
T
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142057
120
14102
S20
P
E
G
T
K
K
V
S
Y
E
R
D
T
K
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38859
116
13545
S20
P
E
G
T
K
K
V
S
Y
D
R
D
T
K
I
Baker's Yeast
Sacchar. cerevisiae
P38902
120
13597
K20
G
E
G
E
S
K
L
K
I
D
P
D
T
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.6
61.2
N.A.
N.A.
99.1
N.A.
N.A.
97.4
N.A.
31.6
30.7
N.A.
76.9
76
65.5
79.4
Protein Similarity:
100
27.6
61.2
N.A.
N.A.
99.1
N.A.
N.A.
97.4
N.A.
52.1
47.8
N.A.
88
90.5
76.2
90.6
P-Site Identity:
100
86.6
100
N.A.
N.A.
100
N.A.
N.A.
100
N.A.
0
20
N.A.
66.6
66.6
53.3
86.6
P-Site Similarity:
100
93.3
100
N.A.
N.A.
100
N.A.
N.A.
100
N.A.
20
40
N.A.
73.3
80
60
93.3
Percent
Protein Identity:
N.A.
49.1
N.A.
46.1
45.8
N.A.
Protein Similarity:
N.A.
71.6
N.A.
67.5
62.5
N.A.
P-Site Identity:
N.A.
46.6
N.A.
46.6
53.3
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
80
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
8
8
8
0
0
0
0
0
15
0
86
8
0
0
% D
% Glu:
0
79
0
65
0
0
8
8
0
36
8
8
0
0
0
% E
% Phe:
43
0
0
0
0
0
15
0
0
0
0
0
15
0
0
% F
% Gly:
8
0
86
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
58
15
58
0
0
0
0
0
15
% I
% Lys:
0
0
0
0
79
86
0
8
15
0
50
0
0
86
0
% K
% Leu:
8
8
0
0
0
0
8
0
8
0
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
43
0
0
0
0
0
% N
% Pro:
15
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
8
0
8
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
22
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
15
0
8
0
36
0
0
0
8
79
0
8
% T
% Val:
8
0
0
0
8
0
15
8
0
0
8
0
0
8
65
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
0
0
0
0
8
15
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _