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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2J
All Species:
42.12
Human Site:
T78
Identified Species:
71.28
UniProt:
P52435
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52435
NP_006225.1
117
13293
T78
I
I
I
R
V
Q
T
T
P
D
Y
S
P
Q
E
Chimpanzee
Pan troglodytes
XP_001135267
398
41732
T317
I
I
I
E
X
Q
T
T
P
D
Y
S
P
Q
E
Rhesus Macaque
Macaca mulatta
XP_001114618
191
20609
T152
I
I
I
R
V
Q
T
T
P
D
Y
S
P
Q
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O08740
117
13233
T78
I
I
I
R
V
Q
T
T
P
D
Y
S
P
Q
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514119
117
13370
T78
I
I
I
R
V
Q
T
T
P
D
Y
S
P
Q
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5XK67
114
13106
F80
G
I
P
A
V
E
P
F
R
R
G
L
N
E
L
Zebra Danio
Brachydanio rerio
Q6DRI4
112
12737
N84
E
P
L
R
N
G
L
N
N
L
T
D
V
C
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJE4
117
13367
T78
F
V
I
R
I
Q
T
T
A
D
Y
S
P
Q
E
Honey Bee
Apis mellifera
XP_624001
117
13510
T78
F
V
I
R
I
Q
T
T
S
D
Y
T
P
H
E
Nematode Worm
Caenorhab. elegans
Q9XVH6
122
13678
T77
I
L
L
R
I
Q
T
T
N
N
T
T
P
A
D
Sea Urchin
Strong. purpuratus
XP_001197448
117
13241
T78
F
V
L
R
V
Q
T
T
P
D
Y
S
P
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142057
120
14102
T78
I
I
V
R
I
H
T
T
S
Q
S
S
P
T
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38859
116
13545
T78
I
I
V
R
I
H
T
T
S
Q
S
S
P
M
Q
Baker's Yeast
Sacchar. cerevisiae
P38902
120
13597
T78
F
K
L
R
I
Q
T
T
E
G
Y
D
P
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.6
61.2
N.A.
N.A.
99.1
N.A.
N.A.
97.4
N.A.
31.6
30.7
N.A.
76.9
76
65.5
79.4
Protein Similarity:
100
27.6
61.2
N.A.
N.A.
99.1
N.A.
N.A.
97.4
N.A.
52.1
47.8
N.A.
88
90.5
76.2
90.6
P-Site Identity:
100
86.6
100
N.A.
N.A.
100
N.A.
N.A.
100
N.A.
13.3
6.6
N.A.
73.3
60
40
80
P-Site Similarity:
100
86.6
100
N.A.
N.A.
100
N.A.
N.A.
100
N.A.
26.6
20
N.A.
86.6
80
80
93.3
Percent
Protein Identity:
N.A.
49.1
N.A.
46.1
45.8
N.A.
Protein Similarity:
N.A.
71.6
N.A.
67.5
62.5
N.A.
P-Site Identity:
N.A.
46.6
N.A.
46.6
40
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
66.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
58
0
15
0
0
15
% D
% Glu:
8
0
0
8
0
8
0
0
8
0
0
0
0
8
58
% E
% Phe:
29
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
8
0
0
0
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
15
0
0
0
0
0
0
0
8
0
% H
% Ile:
58
58
50
0
43
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
8
% K
% Leu:
0
8
29
0
0
0
8
0
0
8
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
8
0
0
8
15
8
0
0
8
0
0
% N
% Pro:
0
8
8
0
0
0
8
0
43
0
0
0
86
0
0
% P
% Gln:
0
0
0
0
0
72
0
0
0
15
0
0
0
50
15
% Q
% Arg:
0
0
0
86
0
0
0
0
8
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
22
0
15
65
0
0
0
% S
% Thr:
0
0
0
0
0
0
86
86
0
0
15
15
0
8
0
% T
% Val:
0
22
15
0
43
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
65
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _