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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2J
All Species:
47.58
Human Site:
Y61
Identified Species:
80.51
UniProt:
P52435
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52435
NP_006225.1
117
13293
Y61
P
Q
V
L
F
A
G
Y
K
V
P
H
P
L
E
Chimpanzee
Pan troglodytes
XP_001135267
398
41732
Y300
P
Q
V
L
F
A
G
Y
K
V
P
H
P
L
E
Rhesus Macaque
Macaca mulatta
XP_001114618
191
20609
Y135
P
Q
V
L
F
A
G
Y
K
V
P
H
P
L
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O08740
117
13233
Y61
P
Q
V
L
F
A
G
Y
K
V
P
H
P
L
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514119
117
13370
Y61
P
Q
V
L
L
Q
E
Y
K
V
P
H
P
L
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5XK67
114
13106
T62
S
I
T
H
P
S
E
T
K
I
N
F
R
I
Q
Zebra Danio
Brachydanio rerio
Q6DRI4
112
12737
I67
E
S
K
I
N
F
R
I
Q
T
R
D
G
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJE4
117
13367
Y61
P
N
V
L
F
A
G
Y
K
V
P
H
P
L
E
Honey Bee
Apis mellifera
XP_624001
117
13510
Y61
P
Q
V
L
F
A
G
Y
K
V
P
H
P
L
E
Nematode Worm
Caenorhab. elegans
Q9XVH6
122
13678
Y60
P
E
V
L
F
A
G
Y
K
N
P
H
P
L
E
Sea Urchin
Strong. purpuratus
XP_001197448
117
13241
Y61
P
Q
V
L
F
A
G
Y
K
V
P
H
P
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142057
120
14102
Y61
P
N
V
L
F
A
G
Y
K
L
P
H
P
L
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38859
116
13545
Y61
E
N
V
L
F
A
G
Y
Q
L
P
H
P
L
K
Baker's Yeast
Sacchar. cerevisiae
P38902
120
13597
Y61
R
K
V
L
F
A
A
Y
K
V
E
H
P
F
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.6
61.2
N.A.
N.A.
99.1
N.A.
N.A.
97.4
N.A.
31.6
30.7
N.A.
76.9
76
65.5
79.4
Protein Similarity:
100
27.6
61.2
N.A.
N.A.
99.1
N.A.
N.A.
97.4
N.A.
52.1
47.8
N.A.
88
90.5
76.2
90.6
P-Site Identity:
100
100
100
N.A.
N.A.
100
N.A.
N.A.
80
N.A.
6.6
0
N.A.
93.3
100
86.6
100
P-Site Similarity:
100
100
100
N.A.
N.A.
100
N.A.
N.A.
80
N.A.
33.3
20
N.A.
93.3
100
93.3
100
Percent
Protein Identity:
N.A.
49.1
N.A.
46.1
45.8
N.A.
Protein Similarity:
N.A.
71.6
N.A.
67.5
62.5
N.A.
P-Site Identity:
N.A.
80
N.A.
66.6
60
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
86.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
79
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
15
8
0
0
0
0
15
0
0
0
8
0
0
0
65
% E
% Phe:
0
0
0
0
79
8
0
0
0
0
0
8
0
8
8
% F
% Gly:
0
0
0
0
0
0
72
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
86
0
0
0
% H
% Ile:
0
8
0
8
0
0
0
8
0
8
0
0
0
8
0
% I
% Lys:
0
8
8
0
0
0
0
0
86
0
0
0
0
0
8
% K
% Leu:
0
0
0
86
8
0
0
0
0
15
0
0
0
79
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
22
0
0
8
0
0
0
0
8
8
0
0
0
0
% N
% Pro:
72
0
0
0
8
0
0
0
0
0
79
0
86
0
8
% P
% Gln:
0
50
0
0
0
8
0
0
15
0
0
0
0
0
15
% Q
% Arg:
8
0
0
0
0
0
8
0
0
0
8
0
8
0
0
% R
% Ser:
8
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
8
0
8
0
0
0
0
0
% T
% Val:
0
0
86
0
0
0
0
0
0
65
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
86
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _