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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGDIA
All Species:
29.7
Human Site:
Y175
Identified Species:
59.39
UniProt:
P52565
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52565
NP_004300.1
204
23207
Y175
G
M
L
A
R
G
S
Y
S
I
K
S
R
F
T
Chimpanzee
Pan troglodytes
XP_001164704
183
21106
S155
M
L
A
R
G
S
Y
S
I
K
S
R
F
T
D
Rhesus Macaque
Macaca mulatta
XP_001112043
178
20308
S150
D
Y
M
V
G
S
Y
S
I
K
S
R
F
T
D
Dog
Lupus familis
XP_849933
204
23375
Y175
G
M
L
A
R
G
S
Y
N
I
K
S
R
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99PT1
204
23389
Y175
G
M
L
A
R
G
S
Y
N
I
K
S
R
F
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515491
219
25235
Y190
G
V
L
V
R
G
H
Y
R
I
K
S
F
F
T
Chicken
Gallus gallus
NP_001074340
204
23256
Y175
G
M
L
A
R
G
S
Y
N
I
K
S
K
F
T
Frog
Xenopus laevis
NP_001085674
204
23448
Y175
G
M
L
A
R
G
C
Y
N
I
K
S
L
F
T
Zebra Danio
Brachydanio rerio
NP_998626
203
23057
Y174
G
M
L
A
R
G
T
Y
N
L
K
S
K
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20496
191
21900
G163
P
S
G
M
M
H
R
G
K
Y
K
V
Y
S
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SFC6
240
27213
Y210
G
M
F
A
R
G
S
Y
S
A
R
T
K
F
L
Baker's Yeast
Sacchar. cerevisiae
Q12434
202
23120
R173
A
P
S
G
F
L
A
R
G
N
Y
S
A
V
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.7
87.2
97.5
N.A.
97
N.A.
N.A.
62
91.1
78.4
81.3
N.A.
N.A.
N.A.
37.7
N.A.
Protein Similarity:
100
89.7
87.2
99.5
N.A.
99.5
N.A.
N.A.
76.2
97.5
88.2
91.1
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
100
0
0
93.3
N.A.
93.3
N.A.
N.A.
66.6
86.6
80
73.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
6.6
6.6
100
N.A.
100
N.A.
N.A.
73.3
100
86.6
100
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.3
39.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.4
61.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
59
0
0
9
0
0
9
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
0
9
0
0
0
0
0
0
0
25
67
0
% F
% Gly:
67
0
9
9
17
67
0
9
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
17
50
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
17
67
0
25
0
9
% K
% Leu:
0
9
59
0
0
9
0
0
0
9
0
0
9
0
9
% L
% Met:
9
59
9
9
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
42
9
0
0
0
0
0
% N
% Pro:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
67
0
9
9
9
0
9
17
25
0
0
% R
% Ser:
0
9
9
0
0
17
42
17
17
0
17
67
0
9
9
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
9
0
17
59
% T
% Val:
0
9
0
17
0
0
0
0
0
0
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
17
67
0
9
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _