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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGDIB
All Species:
24.85
Human Site:
Y130
Identified Species:
49.7
UniProt:
P52566
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52566
NP_001166.3
201
22988
Y130
L
K
Y
V
Q
H
T
Y
R
T
G
V
K
V
D
Chimpanzee
Pan troglodytes
XP_001164704
183
21106
R113
K
Y
I
Q
H
T
Y
R
K
G
V
K
I
D
K
Rhesus Macaque
Macaca mulatta
XP_001090606
198
22401
H128
S
G
L
K
Y
V
Q
H
T
Y
R
T
G
V
K
Dog
Lupus familis
XP_543793
200
22812
Y129
L
K
Y
V
Q
H
T
Y
R
T
G
V
K
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q61599
200
22832
Y129
L
K
Y
V
Q
H
T
Y
R
T
G
M
R
V
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515491
219
25235
Y148
L
K
Y
L
H
H
T
Y
R
K
G
L
R
V
D
Chicken
Gallus gallus
XP_416182
200
22867
Y129
L
K
Y
V
Q
H
T
Y
R
T
G
V
K
V
D
Frog
Xenopus laevis
NP_001080660
200
22605
Y129
L
K
Y
V
Q
H
A
Y
R
A
G
V
R
V
A
Zebra Danio
Brachydanio rerio
NP_957451
204
23390
Y127
L
K
Y
V
H
Q
T
Y
K
K
G
L
R
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20496
191
21900
K121
S
G
L
H
Y
K
H
K
V
K
R
S
G
I
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SFC6
240
27213
W168
L
R
Y
T
N
T
V
W
K
T
G
V
K
V
D
Baker's Yeast
Sacchar. cerevisiae
Q12434
202
23120
K131
L
R
Y
V
Q
Y
I
K
K
A
G
I
A
V
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.7
70.1
94
N.A.
87.5
N.A.
N.A.
60.2
91.5
79.5
71.5
N.A.
N.A.
N.A.
39.7
N.A.
Protein Similarity:
100
74.1
77.6
95
N.A.
93.5
N.A.
N.A.
73.5
95
87.5
82.3
N.A.
N.A.
N.A.
55.2
N.A.
P-Site Identity:
100
0
6.6
100
N.A.
86.6
N.A.
N.A.
66.6
100
73.3
53.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
6.6
13.3
100
N.A.
100
N.A.
N.A.
86.6
100
80
80
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.7
36.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.5
58.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
17
0
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
67
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
17
0
0
0
0
0
0
0
9
75
0
17
0
0
% G
% His:
0
0
0
9
25
50
9
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
9
0
0
0
0
9
9
9
0
% I
% Lys:
9
59
0
9
0
9
0
17
34
25
0
9
34
0
17
% K
% Leu:
75
0
17
9
0
0
0
0
0
0
0
17
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
50
9
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
17
0
0
0
0
0
9
50
0
17
0
34
0
0
% R
% Ser:
17
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% S
% Thr:
0
0
0
9
0
17
50
0
9
42
0
9
0
0
9
% T
% Val:
0
0
0
59
0
9
9
0
9
0
9
42
0
75
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
9
75
0
17
9
9
59
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _