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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC7A2
All Species:
16.97
Human Site:
T459
Identified Species:
41.48
UniProt:
P52569
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52569
NP_003037.3
658
71673
T459
L
G
S
S
P
R
V
T
S
K
S
E
S
Q
V
Chimpanzee
Pan troglodytes
XP_001142615
756
81839
T557
L
G
S
S
P
R
V
T
S
K
S
E
S
Q
V
Rhesus Macaque
Macaca mulatta
XP_001098500
629
67607
M443
Q
P
N
L
V
Y
Q
M
A
S
T
S
D
E
L
Dog
Lupus familis
XP_848421
658
71396
T459
L
G
S
C
A
S
A
T
S
K
S
E
S
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
P18581
657
71848
T458
L
E
S
C
T
N
A
T
L
K
S
E
S
Q
V
Rat
Rattus norvegicus
B5D5N9
657
71676
T458
L
E
S
C
T
N
A
T
S
K
S
E
S
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509155
661
71506
A458
A
L
A
A
A
K
P
A
T
K
S
E
S
Q
L
Chicken
Gallus gallus
B3TP03
654
71198
S458
L
A
A
S
K
R
E
S
A
V
S
E
S
Q
I
Frog
Xenopus laevis
Q6DCE8
622
66913
P436
V
L
L
L
R
Y
Q
P
Q
T
D
F
G
K
S
Zebra Danio
Brachydanio rerio
Q5PR34
640
69447
E452
E
G
K
E
E
V
G
E
S
E
L
T
E
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
58.9
91.9
N.A.
87.6
88.7
N.A.
78
74.1
59.8
67.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
86.5
73.7
96.3
N.A.
94.5
94.5
N.A.
86.9
84.8
73.7
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
73.3
N.A.
60
66.6
N.A.
33.3
46.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
73.3
N.A.
60
66.6
N.A.
66.6
73.3
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
20
10
20
0
30
10
20
0
0
0
0
0
0
% A
% Cys:
0
0
0
30
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% D
% Glu:
10
20
0
10
10
0
10
10
0
10
0
70
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
40
0
0
0
0
10
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
10
0
10
10
0
0
0
60
0
0
0
10
0
% K
% Leu:
60
20
10
20
0
0
0
0
10
0
10
0
0
0
20
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
20
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
20
0
10
10
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
20
0
10
0
0
0
0
70
0
% Q
% Arg:
0
0
0
0
10
30
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
50
30
0
10
0
10
50
10
70
10
70
10
10
% S
% Thr:
0
0
0
0
20
0
0
50
10
10
10
10
0
0
0
% T
% Val:
10
0
0
0
10
10
20
0
0
10
0
0
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _