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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGFG1 All Species: 15.45
Human Site: S162 Identified Species: 28.33
UniProt: P52594 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52594 NP_001128660.1 562 58260 S162 P E V K P L K S L L G D S A P
Chimpanzee Pan troglodytes XP_001137107 562 58200 S162 P E V K P L K S L L G D S A P
Rhesus Macaque Macaca mulatta XP_001111247 517 53144 Q119 S P V V G R S Q G Q Q Q E K K
Dog Lupus familis XP_534592 509 52244 S110 H L N K G T P S Q S P V V G R
Cat Felis silvestris
Mouse Mus musculus Q8K2K6 561 58024 S162 P E V K P L K S L L G E S A P
Rat Rattus norvegicus Q4KLH5 561 58151 S162 P E V K P L K S L L G E S A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505722 521 54086 L122 E V K P L K S L L G E S A P A
Chicken Gallus gallus Q5F413 428 46296 D30 E E N K Y C A D C Q A K G P R
Frog Xenopus laevis NP_001084973 551 57755 S147 H A S I S G S S A S S T S S T
Zebra Danio Brachydanio rerio NP_956129 556 58445 S153 S S A S S T S S T P E V R P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624297 408 45490 E10 S A K R K Q D E K N L K I L R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781727 429 44040 N31 N K T C F E C N Q R G P T Y V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXE7 649 71326 P158 Y H S Y S Q S P P Y D Y Q Y E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 87.5 85.2 N.A. 96.8 96.2 N.A. 82 23.3 70.1 64.9 N.A. N.A. 30.9 N.A. 31.3
Protein Similarity: 100 99.8 87.5 85.4 N.A. 97.3 97.5 N.A. 85.5 37.9 77.2 74.7 N.A. N.A. 45 N.A. 43.9
P-Site Identity: 100 100 6.6 13.3 N.A. 93.3 93.3 N.A. 6.6 13.3 13.3 6.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 6.6 13.3 N.A. 100 100 N.A. 13.3 13.3 20 6.6 N.A. N.A. 6.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 22.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 8 0 0 0 8 0 8 0 8 0 8 31 8 % A
% Cys: 0 0 0 8 0 8 8 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 8 0 0 8 16 0 0 0 % D
% Glu: 16 39 0 0 0 8 0 8 0 0 16 16 8 0 8 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 16 8 0 0 8 8 39 0 8 8 0 % G
% His: 16 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 8 16 47 8 8 31 0 8 0 0 16 0 8 8 % K
% Leu: 0 8 0 0 8 31 0 8 39 31 8 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 16 0 0 0 0 8 0 8 0 0 0 0 0 % N
% Pro: 31 8 0 8 31 0 8 8 8 8 8 8 0 24 31 % P
% Gln: 0 0 0 0 0 16 0 8 16 16 8 8 8 0 0 % Q
% Arg: 0 0 0 8 0 8 0 0 0 8 0 0 8 0 24 % R
% Ser: 24 8 16 8 24 0 39 54 0 16 8 8 39 8 0 % S
% Thr: 0 0 8 0 0 16 0 0 8 0 0 8 8 0 8 % T
% Val: 0 8 39 8 0 0 0 0 0 0 0 16 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 8 8 0 0 0 0 8 0 8 0 16 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _