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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGFG1 All Species: 13.33
Human Site: T177 Identified Species: 24.44
UniProt: P52594 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52594 NP_001128660.1 562 58260 T177 T L H L N K G T P S Q S P V V
Chimpanzee Pan troglodytes XP_001137107 562 58200 T177 T L H L N K G T P S Q S P V V
Rhesus Macaque Macaca mulatta XP_001111247 517 53144 L134 Q F D L L S D L G S D I F A A
Dog Lupus familis XP_534592 509 52244 K125 S Q A Q Q Q E K K Q F D L L S
Cat Felis silvestris
Mouse Mus musculus Q8K2K6 561 58024 T177 A L H L N K G T P S Q S P V V
Rat Rattus norvegicus Q4KLH5 561 58151 T177 A L H L N K G T P T Q S P V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505722 521 54086 P137 L H L N K G T P T Q S P V V A
Chicken Gallus gallus Q5F413 428 46296 V45 W A S W N I G V F I C I R C A
Frog Xenopus laevis NP_001084973 551 57755 T162 P E V K P L K T L L G D G A P
Zebra Danio Brachydanio rerio NP_956129 556 58445 V168 K T L L G E S V P S L H L N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624297 408 45490 N25 E L V S Q S G N K E C F D C H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781727 429 44040 V46 D M T I G T F V C T A C S G I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXE7 649 71326 P173 E R R Y G K I P L G F T G K S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 87.5 85.2 N.A. 96.8 96.2 N.A. 82 23.3 70.1 64.9 N.A. N.A. 30.9 N.A. 31.3
Protein Similarity: 100 99.8 87.5 85.4 N.A. 97.3 97.5 N.A. 85.5 37.9 77.2 74.7 N.A. N.A. 45 N.A. 43.9
P-Site Identity: 100 100 13.3 0 N.A. 93.3 86.6 N.A. 6.6 13.3 6.6 20 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 100 13.3 20 N.A. 93.3 93.3 N.A. 6.6 13.3 6.6 26.6 N.A. N.A. 13.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 22.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 8 0 0 0 0 0 0 0 8 0 0 16 24 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 16 8 0 16 0 % C
% Asp: 8 0 8 0 0 0 8 0 0 0 8 16 8 0 0 % D
% Glu: 16 8 0 0 0 8 8 0 0 8 0 0 0 0 0 % E
% Phe: 0 8 0 0 0 0 8 0 8 0 16 8 8 0 0 % F
% Gly: 0 0 0 0 24 8 47 0 8 8 8 0 16 8 0 % G
% His: 0 8 31 0 0 0 0 0 0 0 0 8 0 0 8 % H
% Ile: 0 0 0 8 0 8 8 0 0 8 0 16 0 0 8 % I
% Lys: 8 0 0 8 8 39 8 8 16 0 0 0 0 8 8 % K
% Leu: 8 39 16 47 8 8 0 8 16 8 8 0 16 8 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 39 0 0 8 0 0 0 0 0 8 0 % N
% Pro: 8 0 0 0 8 0 0 16 39 0 0 8 31 0 8 % P
% Gln: 8 8 0 8 16 8 0 0 0 16 31 0 0 0 0 % Q
% Arg: 0 8 8 0 0 0 0 0 0 0 0 0 8 0 0 % R
% Ser: 8 0 8 8 0 16 8 0 0 39 8 31 8 0 16 % S
% Thr: 16 8 8 0 0 8 8 39 8 16 0 8 0 0 0 % T
% Val: 0 0 16 0 0 0 0 24 0 0 0 0 8 39 31 % V
% Trp: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _