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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HNRNPF
All Species:
10
Human Site:
S374
Identified Species:
24.44
UniProt:
P52597
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52597
NP_001091674.1
415
45672
S374
A
S
N
G
A
Y
S
S
Q
V
M
Q
G
M
G
Chimpanzee
Pan troglodytes
XP_001155889
347
38296
Q307
S
N
G
A
Y
S
S
Q
V
M
Q
G
M
G
V
Rhesus Macaque
Macaca mulatta
XP_001100049
472
51261
H374
A
S
G
G
A
Y
E
H
R
Y
V
E
L
F
L
Dog
Lupus familis
XP_534954
414
45616
S374
A
S
N
G
A
Y
S
S
Q
M
M
Q
G
M
G
Cat
Felis silvestris
Mouse
Mus musculus
O35737
449
49181
H374
A
S
G
G
A
Y
E
H
R
Y
V
E
L
F
L
Rat
Rattus norvegicus
Q794E4
415
45711
S374
A
S
N
G
A
Y
S
S
Q
V
M
Q
G
M
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLR4
701
76929
G536
E
M
N
F
V
L
M
G
G
T
L
N
R
S
G
Frog
Xenopus laevis
Q7ZY29
688
76408
P615
Y
P
S
P
P
G
S
P
S
S
L
G
F
F
P
Zebra Danio
Brachydanio rerio
A1L1G1
714
78118
P626
Y
P
S
P
P
G
S
P
S
N
I
S
Y
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22708
618
69158
T550
E
L
V
A
N
F
T
T
P
E
H
T
V
D
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
67.3
97.8
N.A.
70.8
98
N.A.
N.A.
21.2
20.9
21.4
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
100
83.6
76.4
98.5
N.A.
80.1
99
N.A.
N.A.
34.8
35.1
33.6
N.A.
N.A.
N.A.
35.2
N.A.
P-Site Identity:
100
6.6
33.3
93.3
N.A.
33.3
100
N.A.
N.A.
13.3
6.6
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
26.6
53.3
100
N.A.
53.3
100
N.A.
N.A.
20
20
20
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
20
50
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
20
0
0
0
0
0
20
0
0
10
0
20
0
0
0
% E
% Phe:
0
0
0
10
0
10
0
0
0
0
0
0
10
40
0
% F
% Gly:
0
0
30
50
0
20
0
10
10
0
0
20
30
10
40
% G
% His:
0
0
0
0
0
0
0
20
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
10
0
0
0
0
20
0
20
0
20
% L
% Met:
0
10
0
0
0
0
10
0
0
20
30
0
10
30
0
% M
% Asn:
0
10
40
0
10
0
0
0
0
10
0
10
0
0
10
% N
% Pro:
0
20
0
20
20
0
0
20
10
0
0
0
0
0
20
% P
% Gln:
0
0
0
0
0
0
0
10
30
0
10
30
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
20
0
0
0
10
0
0
% R
% Ser:
10
50
20
0
0
10
60
30
20
10
0
10
0
10
0
% S
% Thr:
0
0
0
0
0
0
10
10
0
10
0
10
0
0
0
% T
% Val:
0
0
10
0
10
0
0
0
10
20
20
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
20
0
0
0
10
50
0
0
0
20
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _