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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HNRNPF All Species: 16.67
Human Site: Y272 Identified Species: 40.74
UniProt: P52597 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52597 NP_001091674.1 415 45672 Y272 S Y C L S G M Y D H R Y G D S
Chimpanzee Pan troglodytes XP_001155889 347 38296 Y208 S G M Y D H R Y G D S E F T V
Rhesus Macaque Macaca mulatta XP_001100049 472 51261 S272 N Y C F S G M S D H R Y G D G
Dog Lupus familis XP_534954 414 45616 Y272 S Y C L S G M Y D H R Y G D G
Cat Felis silvestris
Mouse Mus musculus O35737 449 49181 S272 N Y C F S G M S D H R Y G D G
Rat Rattus norvegicus Q794E4 415 45711 Y272 S Y C L S G M Y D H R Y G D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLR4 701 76929 I430 I P T L P T P I I P V I P P P
Frog Xenopus laevis Q7ZY29 688 76408 A505 S A D R A Y L A A Q K C H K K
Zebra Danio Brachydanio rerio A1L1G1 714 78118 F526 K E R Y V E V F A C S A Q E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22708 618 69158 C448 N E Q A A S A C A A G V H N N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.6 67.3 97.8 N.A. 70.8 98 N.A. N.A. 21.2 20.9 21.4 N.A. N.A. N.A. 21 N.A.
Protein Similarity: 100 83.6 76.4 98.5 N.A. 80.1 99 N.A. N.A. 34.8 35.1 33.6 N.A. N.A. N.A. 35.2 N.A.
P-Site Identity: 100 13.3 73.3 93.3 N.A. 73.3 100 N.A. N.A. 6.6 6.6 0 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 13.3 80 93.3 N.A. 80 100 N.A. N.A. 6.6 26.6 20 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 20 0 10 10 30 10 0 10 0 0 0 % A
% Cys: 0 0 50 0 0 0 0 10 0 10 0 10 0 0 0 % C
% Asp: 0 0 10 0 10 0 0 0 50 10 0 0 0 50 0 % D
% Glu: 0 20 0 0 0 10 0 0 0 0 0 10 0 10 0 % E
% Phe: 0 0 0 20 0 0 0 10 0 0 0 0 10 0 0 % F
% Gly: 0 10 0 0 0 50 0 0 10 0 10 0 50 0 30 % G
% His: 0 0 0 0 0 10 0 0 0 50 0 0 20 0 0 % H
% Ile: 10 0 0 0 0 0 0 10 10 0 0 10 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 10 0 0 10 10 % K
% Leu: 0 0 0 40 0 0 10 0 0 0 0 0 0 0 0 % L
% Met: 0 0 10 0 0 0 50 0 0 0 0 0 0 0 0 % M
% Asn: 30 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % N
% Pro: 0 10 0 0 10 0 10 0 0 10 0 0 10 10 10 % P
% Gln: 0 0 10 0 0 0 0 0 0 10 0 0 10 0 0 % Q
% Arg: 0 0 10 10 0 0 10 0 0 0 50 0 0 0 0 % R
% Ser: 50 0 0 0 50 10 0 20 0 0 20 0 0 0 20 % S
% Thr: 0 0 10 0 0 10 0 0 0 0 0 0 0 10 0 % T
% Val: 0 0 0 0 10 0 10 0 0 0 10 10 0 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 50 0 20 0 10 0 40 0 0 0 50 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _