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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STAT2
All Species:
18.18
Human Site:
S606
Identified Species:
50
UniProt:
P52630
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52630
NP_005410.1
851
97916
S606
L
L
R
F
S
E
S
S
E
G
G
I
T
C
S
Chimpanzee
Pan troglodytes
XP_001168971
851
97916
S606
L
L
R
F
S
E
S
S
E
G
G
I
T
C
S
Rhesus Macaque
Macaca mulatta
XP_001115072
851
97734
S606
L
L
R
F
S
E
S
S
E
G
G
I
T
C
S
Dog
Lupus familis
XP_538232
854
98064
S605
L
L
R
F
S
E
T
S
E
G
G
I
T
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL2
923
105399
S605
L
L
R
F
S
E
T
S
E
G
G
I
T
C
S
Rat
Rattus norvegicus
P52631
770
88021
C550
Q
I
T
W
A
K
F
C
K
E
N
M
A
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6DV79
771
88152
K551
I
T
W
A
K
F
C
K
E
N
M
A
G
K
G
Frog
Xenopus laevis
Q7ZXK3
766
87581
W546
Y
S
G
C
Q
I
T
W
A
K
F
C
K
E
N
Zebra Danio
Brachydanio rerio
XP_693577
835
95562
K601
L
R
F
S
E
S
I
K
D
G
G
I
T
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97
85.4
N.A.
66.5
37
N.A.
N.A.
36.4
36.3
37.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97.8
90.5
N.A.
75.8
55.2
N.A.
N.A.
55.4
54.6
55.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
0
N.A.
N.A.
6.6
0
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
N.A.
13.3
13.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
12
0
0
0
12
0
0
12
12
0
0
% A
% Cys:
0
0
0
12
0
0
12
12
0
0
0
12
0
56
0
% C
% Asp:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
12
56
0
0
67
12
0
0
0
12
0
% E
% Phe:
0
0
12
56
0
12
12
0
0
0
12
0
0
12
0
% F
% Gly:
0
0
12
0
0
0
0
0
0
67
67
0
12
12
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
12
0
0
0
12
12
0
0
0
0
67
0
0
0
% I
% Lys:
0
0
0
0
12
12
0
23
12
12
0
0
12
12
12
% K
% Leu:
67
56
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
12
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
56
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
12
0
12
56
12
34
56
0
0
0
0
0
0
67
% S
% Thr:
0
12
12
0
0
0
34
0
0
0
0
0
67
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
12
12
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _