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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2A1
All Species:
35.45
Human Site:
S281
Identified Species:
70.91
UniProt:
P52655
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52655
NP_056943.1
376
41514
S281
D
G
T
G
D
T
S
S
E
E
D
E
D
E
E
Chimpanzee
Pan troglodytes
XP_001134883
376
41525
S281
D
G
T
G
D
T
S
S
E
E
D
E
D
E
E
Rhesus Macaque
Macaca mulatta
XP_001105227
326
35747
S231
D
G
T
G
D
T
S
S
E
E
D
E
D
E
E
Dog
Lupus familis
XP_854907
397
44313
S302
D
G
T
G
D
T
S
S
E
E
D
E
D
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99PM3
378
41595
S283
D
G
T
G
D
T
S
S
E
E
D
E
D
E
E
Rat
Rattus norvegicus
O08949
377
41544
S282
D
G
T
G
D
T
S
S
E
E
D
E
D
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512353
377
41643
S282
D
G
A
G
D
T
S
S
E
E
D
E
D
E
E
Chicken
Gallus gallus
NP_001026378
338
37389
S243
D
G
A
G
D
T
S
S
E
E
E
E
D
E
E
Frog
Xenopus laevis
NP_001083954
367
40602
E275
A
G
D
T
S
S
E
E
D
E
D
E
D
E
D
Zebra Danio
Brachydanio rerio
NP_997822
369
40798
S274
D
G
A
G
D
T
S
S
E
E
D
E
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52654
366
39250
D275
D
E
S
E
E
S
D
D
N
I
D
N
D
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32773
286
32182
E207
V
K
L
Q
A
K
K
E
K
R
S
A
L
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
86.6
92.4
N.A.
96.5
98.4
N.A.
92.8
81.3
82.1
72.6
N.A.
29.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
86.6
93.1
N.A.
97.8
98.9
N.A.
94.9
82.7
88
82.9
N.A.
47.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
86.6
40
86.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
60
93.3
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
25
0
9
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
84
0
9
0
75
0
9
9
9
0
84
0
84
9
25
% D
% Glu:
0
9
0
9
9
0
9
17
75
84
9
84
9
84
75
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
84
0
75
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
9
9
0
9
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
0
0
0
0
0
0
0
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
0
9
0
9
17
75
75
0
0
9
0
0
0
0
% S
% Thr:
0
0
50
9
0
75
0
0
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _