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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF2A1 All Species: 10.61
Human Site: T265 Identified Species: 21.21
UniProt: P52655 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52655 NP_056943.1 376 41514 T265 P Q A Q P A Q T Q A P L V L Q
Chimpanzee Pan troglodytes XP_001134883 376 41525 T265 P Q A Q P A Q T Q A P L V L Q
Rhesus Macaque Macaca mulatta XP_001105227 326 35747 T215 P Q A Q P A Q T Q A P L V L Q
Dog Lupus familis XP_854907 397 44313 P286 P Q T Q P A Q P Q A P L V L Q
Cat Felis silvestris
Mouse Mus musculus Q99PM3 378 41595 Q267 P Q A Q P A Q Q Q A P L V L Q
Rat Rattus norvegicus O08949 377 41544 Q266 P Q A Q P A Q Q Q A P L V L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512353 377 41643 P266 P Q Q Q P A Q P Q A P L V L Q
Chicken Gallus gallus NP_001026378 338 37389 P227 P Q Q Q Q A Q P Q A P L V L Q
Frog Xenopus laevis NP_001083954 367 40602 T259 Q Q Q G Q Q Q T S I V L Q V D
Zebra Danio Brachydanio rerio NP_997822 369 40798 Q258 Q Q Q Q Q A S Q Q P P M M L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52654 366 39250 D259 L A A A K Q L D G A L D S S D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32773 286 32182 R191 E E D V E K T R K E K E Q I E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 86.6 92.4 N.A. 96.5 98.4 N.A. 92.8 81.3 82.1 72.6 N.A. 29.7 N.A. N.A. N.A.
Protein Similarity: 100 99.7 86.6 93.1 N.A. 97.8 98.9 N.A. 94.9 82.7 88 82.9 N.A. 47.3 N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 86.6 80 26.6 46.6 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 86.6 80 33.3 60 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 50 9 0 75 0 0 0 75 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 9 0 0 0 9 0 0 17 % D
% Glu: 9 9 0 0 9 0 0 0 0 9 0 9 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % I
% Lys: 0 0 0 0 9 9 0 0 9 0 9 0 0 0 0 % K
% Leu: 9 0 0 0 0 0 9 0 0 0 9 75 0 75 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 67 0 0 0 59 0 0 25 0 9 75 0 0 0 0 % P
% Gln: 17 84 34 75 25 17 75 25 75 0 0 0 17 0 75 % Q
% Arg: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 9 0 9 0 0 0 9 9 0 % S
% Thr: 0 0 9 0 0 0 9 34 0 0 0 0 0 0 0 % T
% Val: 0 0 0 9 0 0 0 0 0 0 9 0 67 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _