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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF2A2 All Species: 42.42
Human Site: S18 Identified Species: 77.78
UniProt: P52657 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52657 NP_004483.1 109 12457 S18 L G N S L Q E S L D E L I Q S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001100139 74 8435
Dog Lupus familis XP_864467 106 12111 S18 L G N S L Q E S L D E L I Q I
Cat Felis silvestris
Mouse Mus musculus XP_001476879 109 12483 S18 L G N S L Q E S L D E L I Q S
Rat Rattus norvegicus O08950 109 12455 S18 L G N S L Q E S L D E L I Q S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509605 109 12411 S18 L G N S L Q E S L D E L I Q S
Chicken Gallus gallus NP_001075177 109 12381 S18 L G N S L Q E S L D E L I Q S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001018441 109 12381 S18 L G N S L Q E S L D E L I Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52656 106 12175 S18 L G N T L Q E S L D E L I Q Y
Honey Bee Apis mellifera XP_623063 112 12716 S18 L G N T L Q E S L D E L I Q Y
Nematode Worm Caenorhab. elegans Q9NEX2 113 12887 T21 L G Q A L Q K T L D D F V G D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39236 106 12121 T19 I G M C L T E T L D E M V Q S
Baker's Yeast Sacchar. cerevisiae P32774 122 13440 A22 I G N S L V D A L D T L I S D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 67.8 96.3 N.A. 98.1 99 N.A. 97.2 96.3 N.A. 93.5 N.A. 75.2 74.1 45.1 N.A.
Protein Similarity: 100 N.A. 67.8 97.2 N.A. 99 100 N.A. 99 98.1 N.A. 96.3 N.A. 84.4 83.9 64.5 N.A.
P-Site Identity: 100 N.A. 0 93.3 N.A. 100 100 N.A. 100 100 N.A. 93.3 N.A. 86.6 86.6 40 N.A.
P-Site Similarity: 100 N.A. 0 93.3 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 93.3 93.3 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 49.5 35.2 N.A.
Protein Similarity: N.A. N.A. N.A. 71.5 57.3 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 93 8 0 0 0 16 % D
% Glu: 0 0 0 0 0 0 77 0 0 0 77 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 93 0 0 0 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 16 0 0 0 0 0 0 0 0 0 0 0 77 0 8 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 77 0 0 0 93 0 0 0 93 0 0 77 0 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 77 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 77 0 0 0 0 0 0 0 77 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 62 0 0 0 70 0 0 0 0 0 8 47 % S
% Thr: 0 0 0 16 0 8 0 16 0 0 8 0 0 0 8 % T
% Val: 0 0 0 0 0 8 0 0 0 0 0 0 16 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _