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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF2A2 All Species: 45.15
Human Site: Y65 Identified Species: 82.78
UniProt: P52657 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52657 NP_004483.1 109 12457 Y65 F R G S L N T Y R F C D N V W
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001100139 74 8435 D34 L N T Y R F C D N V W T F V L
Dog Lupus familis XP_864467 106 12111 Y62 F R G S L N T Y R F C D N V W
Cat Felis silvestris
Mouse Mus musculus XP_001476879 109 12483 Y65 F R G S L N T Y R F C D N V W
Rat Rattus norvegicus O08950 109 12455 Y65 F R G S L N T Y R F C D N V W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509605 109 12411 Y65 F R G S L N T Y R F C D N V W
Chicken Gallus gallus NP_001075177 109 12381 Y65 F R G S L N T Y R F C D N V W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001018441 109 12381 Y65 F R G S L N T Y R F C D N V W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52656 106 12175 Y66 K A G K L N T Y R F C D N V W
Honey Bee Apis mellifera XP_623063 112 12716 Y66 K A G K L N T Y R F C D N V W
Nematode Worm Caenorhab. elegans Q9NEX2 113 12887 Y69 R A D K L R A Y R Y C D N V W
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39236 106 12121 Y66 I K G H L H T Y R F C D N V W
Baker's Yeast Sacchar. cerevisiae P32774 122 13440 Y69 V K G N L D T Y G F C D D V W
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 67.8 96.3 N.A. 98.1 99 N.A. 97.2 96.3 N.A. 93.5 N.A. 75.2 74.1 45.1 N.A.
Protein Similarity: 100 N.A. 67.8 97.2 N.A. 99 100 N.A. 99 98.1 N.A. 96.3 N.A. 84.4 83.9 64.5 N.A.
P-Site Identity: 100 N.A. 6.6 100 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 80 80 53.3 N.A.
P-Site Similarity: 100 N.A. 6.6 100 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 80 80 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 49.5 35.2 N.A.
Protein Similarity: N.A. N.A. N.A. 71.5 57.3 N.A.
P-Site Identity: N.A. N.A. N.A. 73.3 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 0 0 0 0 8 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 93 0 0 0 0 % C
% Asp: 0 0 8 0 0 8 0 8 0 0 0 93 8 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 54 0 0 0 0 8 0 0 0 85 0 0 8 0 0 % F
% Gly: 0 0 85 0 0 0 0 0 8 0 0 0 0 0 0 % G
% His: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 16 16 0 24 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 0 93 0 0 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 0 70 0 0 8 0 0 0 85 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 54 0 0 8 8 0 0 85 0 0 0 0 0 0 % R
% Ser: 0 0 0 54 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 8 0 0 0 85 0 0 0 0 8 0 0 0 % T
% Val: 8 0 0 0 0 0 0 0 0 8 0 0 0 100 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 93 % W
% Tyr: 0 0 0 8 0 0 0 93 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _