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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH6
All Species:
37.27
Human Site:
S1297
Identified Species:
58.57
UniProt:
P52701
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52701
NP_000170.1
1360
152786
S1297
I
K
G
A
C
P
K
S
Y
G
F
N
A
A
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113749
1360
152750
S1297
I
K
G
A
C
P
K
S
Y
G
F
N
A
A
R
Dog
Lupus familis
XP_531814
1283
145094
V1235
L
A
N
L
P
E
E
V
I
Q
K
G
H
R
K
Cat
Felis silvestris
Mouse
Mus musculus
P54276
1358
151058
S1295
I
K
G
A
C
P
K
S
Y
G
F
N
A
A
R
Rat
Rattus norvegicus
XP_002726765
1361
151628
S1298
I
K
G
A
C
P
K
S
Y
G
F
N
A
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419359
1466
164165
S1403
I
E
G
A
C
P
K
S
Y
G
F
N
A
A
R
Frog
Xenopus laevis
NP_001089247
1340
149481
S1279
I
K
G
A
C
P
K
S
Y
G
F
N
A
A
R
Zebra Danio
Brachydanio rerio
NP_878280
1369
153213
S1306
I
R
G
A
C
P
K
S
Y
G
F
N
A
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUM0
1190
133117
S1144
I
K
R
A
Y
E
L
S
K
K
V
E
A
I
A
Honey Bee
Apis mellifera
XP_392346
1120
127429
L1074
Y
G
F
N
A
A
R
L
G
G
V
P
A
V
I
Nematode Worm
Caenorhab. elegans
NP_491163
1186
133609
Q1140
K
L
A
G
I
D
H
Q
V
V
R
N
A
Y
L
Sea Urchin
Strong. purpuratus
XP_797647
1335
149141
S1274
V
G
G
A
C
P
K
S
Y
G
F
N
A
A
R
Poplar Tree
Populus trichocarpa
XP_002320307
1288
142120
E1238
G
R
H
R
K
G
S
E
G
K
L
A
I
Q
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04716
1324
146779
S1244
T
P
G
A
C
P
K
S
Y
G
V
N
V
A
R
Baker's Yeast
Sacchar. cerevisiae
Q03834
1242
140062
S1196
S
V
P
G
G
L
Q
S
D
F
V
R
I
A
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.3
88.1
N.A.
85.8
86.4
N.A.
N.A.
64.2
66.5
60
N.A.
39
41.2
34.4
48.6
Protein Similarity:
100
N.A.
98.6
91.3
N.A.
92.1
92.8
N.A.
N.A.
75.4
79.9
74.9
N.A.
57.6
58
52.7
66.6
P-Site Identity:
100
N.A.
100
0
N.A.
100
100
N.A.
N.A.
93.3
100
93.3
N.A.
33.3
13.3
13.3
86.6
P-Site Similarity:
100
N.A.
100
20
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
33.3
20
13.3
93.3
Percent
Protein Identity:
36.1
N.A.
N.A.
33.2
29
N.A.
Protein Similarity:
52
N.A.
N.A.
51.4
49.1
N.A.
P-Site Identity:
0
N.A.
N.A.
73.3
13.3
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
73.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
67
7
7
0
0
0
0
0
7
74
67
7
% A
% Cys:
0
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% D
% Glu:
0
7
0
0
0
14
7
7
0
0
0
7
0
0
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
7
54
0
0
0
0
% F
% Gly:
7
14
60
14
7
7
0
0
14
67
0
7
0
0
0
% G
% His:
0
0
7
0
0
0
7
0
0
0
0
0
7
0
0
% H
% Ile:
54
0
0
0
7
0
0
0
7
0
0
0
14
7
7
% I
% Lys:
7
40
0
0
7
0
60
0
7
14
7
0
0
0
7
% K
% Leu:
7
7
0
7
0
7
7
7
0
0
7
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
0
0
0
0
0
0
0
67
0
0
0
% N
% Pro:
0
7
7
0
7
60
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
7
7
0
7
0
0
0
7
0
% Q
% Arg:
0
14
7
7
0
0
7
0
0
0
7
7
0
7
60
% R
% Ser:
7
0
0
0
0
0
7
74
0
0
0
0
0
0
7
% S
% Thr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
7
7
0
0
0
0
0
7
7
7
27
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
7
0
0
0
60
0
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _