KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH6
All Species:
15.15
Human Site:
S91
Identified Species:
23.81
UniProt:
P52701
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52701
NP_000170.1
1360
152786
S91
A
P
T
S
C
D
F
S
P
G
D
L
V
W
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113749
1360
152750
S91
A
P
T
S
C
D
F
S
P
G
D
L
V
W
A
Dog
Lupus familis
XP_531814
1283
145094
P92
G
H
F
Y
S
S
K
P
E
I
L
R
A
M
Q
Cat
Felis silvestris
Mouse
Mus musculus
P54276
1358
151058
S91
P
P
S
S
C
D
F
S
P
G
D
L
V
W
A
Rat
Rattus norvegicus
XP_002726765
1361
151628
G91
S
S
C
D
F
S
P
G
D
L
V
W
A
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419359
1466
164165
S206
R
G
V
S
G
V
Y
S
P
G
D
L
V
W
A
Frog
Xenopus laevis
NP_001089247
1340
149481
G91
L
V
W
A
K
M
L
G
H
P
W
W
P
S
L
Zebra Danio
Brachydanio rerio
NP_878280
1369
153213
V91
V
F
S
A
G
S
L
V
W
A
K
M
E
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUM0
1190
133117
T14
T
S
V
G
G
T
P
T
N
T
L
L
N
Y
F
Honey Bee
Apis mellifera
XP_392346
1120
127429
Nematode Worm
Caenorhab. elegans
NP_491163
1186
133609
S10
K
R
Q
S
S
L
M
S
F
F
T
K
T
P
K
Sea Urchin
Strong. purpuratus
XP_797647
1335
149141
C91
N
H
P
T
L
E
K
C
T
K
K
E
G
R
K
Poplar Tree
Populus trichocarpa
XP_002320307
1288
142120
K93
T
P
S
P
S
P
S
K
V
G
V
Y
G
K
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04716
1324
146779
T91
S
P
S
P
G
P
D
T
P
S
P
V
Q
S
K
Baker's Yeast
Sacchar. cerevisiae
Q03834
1242
140062
N66
A
T
D
K
I
T
K
N
P
Q
G
G
K
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.3
88.1
N.A.
85.8
86.4
N.A.
N.A.
64.2
66.5
60
N.A.
39
41.2
34.4
48.6
Protein Similarity:
100
N.A.
98.6
91.3
N.A.
92.1
92.8
N.A.
N.A.
75.4
79.9
74.9
N.A.
57.6
58
52.7
66.6
P-Site Identity:
100
N.A.
100
0
N.A.
86.6
0
N.A.
N.A.
60
0
0
N.A.
6.6
0
13.3
0
P-Site Similarity:
100
N.A.
100
0
N.A.
93.3
6.6
N.A.
N.A.
66.6
6.6
20
N.A.
20
0
13.3
13.3
Percent
Protein Identity:
36.1
N.A.
N.A.
33.2
29
N.A.
Protein Similarity:
52
N.A.
N.A.
51.4
49.1
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
20
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
14
0
0
0
0
0
7
0
0
14
0
27
% A
% Cys:
0
0
7
0
20
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
7
0
20
7
0
7
0
27
0
0
0
0
% D
% Glu:
0
0
0
0
0
7
0
0
7
0
0
7
7
0
7
% E
% Phe:
0
7
7
0
7
0
20
0
7
7
0
0
0
0
7
% F
% Gly:
7
7
0
7
27
0
0
14
0
34
7
7
14
7
7
% G
% His:
0
14
0
0
0
0
0
0
7
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
7
0
0
7
7
0
20
7
0
7
14
7
7
14
20
% K
% Leu:
7
0
0
0
7
7
14
0
0
7
14
34
0
0
7
% L
% Met:
0
0
0
0
0
7
7
0
0
0
0
7
0
7
7
% M
% Asn:
7
0
0
0
0
0
0
7
7
0
0
0
7
0
0
% N
% Pro:
7
34
7
14
0
14
14
7
40
7
7
0
7
7
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
7
0
0
7
0
7
% Q
% Arg:
7
7
0
0
0
0
0
0
0
0
0
7
0
7
0
% R
% Ser:
14
14
27
34
20
20
7
34
0
7
0
0
0
14
0
% S
% Thr:
14
7
14
7
0
14
0
14
7
7
7
0
7
7
0
% T
% Val:
7
7
14
0
0
7
0
7
7
0
14
7
27
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
7
0
7
14
0
27
0
% W
% Tyr:
0
0
0
7
0
0
7
0
0
0
0
7
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _