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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH6
All Species:
23.64
Human Site:
T987
Identified Species:
37.14
UniProt:
P52701
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52701
NP_000170.1
1360
152786
T987
E
I
P
E
N
F
T
T
R
N
L
P
E
E
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113749
1360
152750
T987
E
I
P
E
N
F
T
T
R
N
L
P
E
E
Y
Dog
Lupus familis
XP_531814
1283
145094
D948
I
N
A
E
E
R
R
D
V
S
L
K
D
C
M
Cat
Felis silvestris
Mouse
Mus musculus
P54276
1358
151058
T984
E
I
P
E
N
F
A
T
R
N
L
P
E
E
Y
Rat
Rattus norvegicus
XP_002726765
1361
151628
T987
E
I
P
E
N
F
A
T
R
N
L
P
E
E
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419359
1466
164165
S1093
E
I
P
E
T
A
T
S
R
N
L
P
E
E
Y
Frog
Xenopus laevis
NP_001089247
1340
149481
D967
E
I
P
E
N
I
A
D
R
N
L
P
E
E
Y
Zebra Danio
Brachydanio rerio
NP_878280
1369
153213
E988
E
V
P
E
S
V
S
E
R
S
L
P
E
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUM0
1190
133117
N862
Q
H
A
E
D
T
R
N
M
V
L
K
D
L
A
Honey Bee
Apis mellifera
XP_392346
1120
127429
S792
K
R
Y
Y
T
A
E
S
K
E
L
L
S
R
Q
Nematode Worm
Caenorhab. elegans
NP_491163
1186
133609
K858
A
V
E
K
E
K
S
K
L
G
D
D
A
T
R
Sea Urchin
Strong. purpuratus
XP_797647
1335
149141
S959
E
I
P
E
S
A
L
S
R
H
I
P
E
E
Y
Poplar Tree
Populus trichocarpa
XP_002320307
1288
142120
Y952
L
I
V
C
F
C
K
Y
H
D
K
W
R
Q
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04716
1324
146779
G941
E
V
P
E
S
L
S
G
S
V
P
H
D
Y
E
Baker's Yeast
Sacchar. cerevisiae
Q03834
1242
140062
T914
C
L
L
A
I
T
R
T
S
E
Y
L
G
A
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.3
88.1
N.A.
85.8
86.4
N.A.
N.A.
64.2
66.5
60
N.A.
39
41.2
34.4
48.6
Protein Similarity:
100
N.A.
98.6
91.3
N.A.
92.1
92.8
N.A.
N.A.
75.4
79.9
74.9
N.A.
57.6
58
52.7
66.6
P-Site Identity:
100
N.A.
100
13.3
N.A.
93.3
93.3
N.A.
N.A.
80
80
60
N.A.
13.3
6.6
0
60
P-Site Similarity:
100
N.A.
100
26.6
N.A.
93.3
93.3
N.A.
N.A.
86.6
80
86.6
N.A.
33.3
26.6
20
86.6
Percent
Protein Identity:
36.1
N.A.
N.A.
33.2
29
N.A.
Protein Similarity:
52
N.A.
N.A.
51.4
49.1
N.A.
P-Site Identity:
6.6
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
46.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
14
7
0
20
20
0
0
0
0
0
7
7
7
% A
% Cys:
7
0
0
7
0
7
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
0
0
0
7
0
0
14
0
7
7
7
20
0
0
% D
% Glu:
60
0
7
74
14
0
7
7
0
14
0
0
54
54
7
% E
% Phe:
0
0
0
0
7
27
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
7
0
0
7
0
0
% G
% His:
0
7
0
0
0
0
0
0
7
7
0
7
0
0
0
% H
% Ile:
7
54
0
0
7
7
0
0
0
0
7
0
0
0
0
% I
% Lys:
7
0
0
7
0
7
7
7
7
0
7
14
0
0
0
% K
% Leu:
7
7
7
0
0
7
7
0
7
0
67
14
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% M
% Asn:
0
7
0
0
34
0
0
7
0
40
0
0
0
0
0
% N
% Pro:
0
0
60
0
0
0
0
0
0
0
7
54
0
0
7
% P
% Gln:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% Q
% Arg:
0
7
0
0
0
7
20
0
54
0
0
0
7
7
7
% R
% Ser:
0
0
0
0
20
0
20
20
14
14
0
0
7
0
0
% S
% Thr:
0
0
0
0
14
14
20
34
0
0
0
0
0
7
0
% T
% Val:
0
20
7
0
0
7
0
0
7
14
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
7
7
0
0
0
7
0
0
7
0
0
7
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _