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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF11
All Species:
34.85
Human Site:
S237
Identified Species:
47.92
UniProt:
P52732
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52732
NP_004514.2
1056
119159
S237
A
Y
S
S
R
S
H
S
V
F
S
V
T
I
H
Chimpanzee
Pan troglodytes
XP_507923
1056
119132
S237
A
Y
S
S
R
S
H
S
V
F
S
V
T
I
H
Rhesus Macaque
Macaca mulatta
XP_001087644
853
96218
D91
S
V
V
C
P
I
L
D
E
V
I
M
G
Y
N
Dog
Lupus familis
XP_534964
1334
149091
S519
A
Y
S
S
R
S
H
S
V
F
S
V
T
I
H
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9P6
1052
118008
S236
A
Y
S
S
R
S
H
S
V
F
S
V
T
I
H
Rat
Rattus norvegicus
O55165
796
89797
T34
A
G
H
E
Q
I
L
T
M
D
V
K
L
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90640
1225
138905
A215
S
Q
S
S
R
S
H
A
I
F
T
I
C
I
D
Frog
Xenopus laevis
P28025
1060
119314
S230
A
Y
S
S
R
S
H
S
V
F
S
V
T
I
H
Zebra Danio
Brachydanio rerio
NP_775368
955
106984
V193
D
P
R
N
K
K
G
V
T
I
K
G
L
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46863
1066
121145
T233
A
Q
S
S
R
S
H
T
V
F
S
I
V
V
H
Honey Bee
Apis mellifera
XP_623508
706
80766
Nematode Worm
Caenorhab. elegans
P46873
699
78760
Sea Urchin
Strong. purpuratus
P46872
699
78679
Poplar Tree
Populus trichocarpa
XP_002314206
1066
119757
S262
K
Q
S
S
R
S
H
S
I
F
S
I
T
I
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P82266
1056
119250
S237
K
Q
S
S
R
S
H
S
L
F
S
I
T
I
H
Baker's Yeast
Sacchar. cerevisiae
P28742
1111
125776
T284
D
L
S
S
R
S
H
T
V
F
T
I
T
T
N
Red Bread Mold
Neurospora crassa
P48467
928
102392
G166
V
H
E
E
K
N
R
G
V
Y
V
K
G
L
L
Conservation
Percent
Protein Identity:
100
99.8
77.5
69.3
N.A.
79.7
23.3
N.A.
N.A.
25.3
56.2
47.7
N.A.
33.5
37.1
27.4
29.2
Protein Similarity:
100
99.9
79
73.8
N.A.
89
40.4
N.A.
N.A.
43.5
72.7
63.9
N.A.
55.4
52
42.5
42.8
P-Site Identity:
100
100
0
100
N.A.
100
6.6
N.A.
N.A.
46.6
100
0
N.A.
66.6
0
0
0
P-Site Similarity:
100
100
20
100
N.A.
100
26.6
N.A.
N.A.
80
100
13.3
N.A.
86.6
0
0
0
Percent
Protein Identity:
32.9
N.A.
N.A.
31.9
27.2
27.5
Protein Similarity:
52.3
N.A.
N.A.
51.5
48.6
45.5
P-Site Identity:
73.3
N.A.
N.A.
73.3
53.3
6.6
P-Site Similarity:
86.6
N.A.
N.A.
86.6
80
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
6
0
0
0
0
0
0
0
0
6
0
0
% C
% Asp:
12
0
0
0
0
0
0
6
0
6
0
0
0
0
6
% D
% Glu:
0
0
6
12
0
0
0
0
6
0
0
0
0
6
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
59
0
0
0
0
0
% F
% Gly:
0
6
0
0
0
0
6
6
0
0
0
6
12
6
0
% G
% His:
0
6
6
0
0
0
59
0
0
0
0
0
0
0
48
% H
% Ile:
0
0
0
0
0
12
0
0
12
6
6
30
0
48
0
% I
% Lys:
12
0
0
0
12
6
0
0
0
0
6
12
0
0
0
% K
% Leu:
0
6
0
0
0
0
12
0
6
0
0
0
12
6
6
% L
% Met:
0
0
0
0
0
0
0
0
6
0
0
6
0
0
0
% M
% Asn:
0
0
0
6
0
6
0
0
0
0
0
0
0
0
12
% N
% Pro:
0
6
0
0
6
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
24
0
0
6
0
0
0
0
0
0
0
0
0
6
% Q
% Arg:
0
0
6
0
59
0
6
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
59
59
0
59
0
42
0
0
48
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
18
6
0
12
0
48
6
0
% T
% Val:
6
6
6
0
0
0
0
6
48
6
12
30
6
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
30
0
0
0
0
0
0
0
6
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _