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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 35.45
Human Site: S348 Identified Species: 48.75
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 S348 L N L E E T L S T L E Y A H R
Chimpanzee Pan troglodytes XP_507923 1056 119132 S348 L N L E E T L S T L E Y A H R
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 I196 R N K R G V I I K G L E E I T
Dog Lupus familis XP_534964 1334 149091 S630 L N L E E T L S T L E Y A H R
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 S347 F N L E E T L S T L E Y A H R
Rat Rattus norvegicus O55165 796 89797 Y139 S R S Q N Q Q Y L V R A S Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 N327 S N L E E T L N T L R Y A D R
Frog Xenopus laevis P28025 1060 119314 S341 I N L E E T V S T L D Y A N R
Zebra Danio Brachydanio rerio NP_775368 955 106984 I298 L L T L G R V I K A L V E R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 S345 K D I E E T L S T L E Y A H R
Honey Bee Apis mellifera XP_623508 706 80766 E49 N K E V I I R E R P H D K F T
Nematode Worm Caenorhab. elegans P46873 699 78760 D42 Q V N L N A P D G A A K D F T
Sea Urchin Strong. purpuratus P46872 699 78679 V42 M D E M R G T V Q V T N P N A
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 S373 Q S L E E T L S T L D Y A H R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 S348 H C L E E T L S T L D Y A H R
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 S399 I S M E E T A S T L E Y A T R
Red Bread Mold Neurospora crassa P48467 928 102392 A271 A L G M V I N A L T D G K S S
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 6.6 100 N.A. 93.3 0 N.A. N.A. 73.3 73.3 6.6 N.A. 80 0 0 0
P-Site Similarity: 100 100 13.3 100 N.A. 93.3 26.6 N.A. N.A. 80 100 13.3 N.A. 93.3 0 0 26.6
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 80 N.A. N.A. 80 66.6 0
P-Site Similarity: 93.3 N.A. N.A. 86.6 86.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 0 0 0 6 6 6 0 12 6 6 59 0 6 % A
% Cys: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 0 0 0 0 0 6 0 0 24 6 6 6 0 % D
% Glu: 0 0 12 59 59 0 0 6 0 0 36 6 12 0 0 % E
% Phe: 6 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % F
% Gly: 0 0 6 0 12 6 0 0 6 6 0 6 0 0 6 % G
% His: 6 0 0 0 0 0 0 0 0 0 6 0 0 42 0 % H
% Ile: 12 0 6 0 6 12 6 12 0 0 0 0 0 6 0 % I
% Lys: 6 6 6 0 0 0 0 0 12 0 0 6 12 0 0 % K
% Leu: 24 12 48 12 0 0 48 0 12 59 12 0 0 0 6 % L
% Met: 6 0 6 12 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 6 42 6 0 12 0 6 6 0 0 0 6 0 12 0 % N
% Pro: 0 0 0 0 0 0 6 0 0 6 0 0 6 0 0 % P
% Gln: 12 0 0 6 0 6 6 0 6 0 0 0 0 0 0 % Q
% Arg: 6 6 0 6 6 6 6 0 6 0 12 0 0 6 59 % R
% Ser: 12 12 6 0 0 0 0 53 0 0 0 0 6 6 6 % S
% Thr: 0 0 6 0 0 59 6 0 59 6 6 0 0 6 18 % T
% Val: 0 6 0 6 6 6 12 6 0 12 0 6 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 6 0 0 0 59 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _