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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 16.97
Human Site: S452 Identified Species: 23.33
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 S452 N E L D Q C K S D L Q N K T Q
Chimpanzee Pan troglodytes XP_507923 1056 119132 S452 N E L D Q C K S D L Q N K T Q
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 R283 G A V D K R A R E A G N I N Q
Dog Lupus familis XP_534964 1334 149091 S734 N E L D Q C K S D L Q N K T Q
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 S451 N E L D Q C K S D L Q T K T Q
Rat Rattus norvegicus O55165 796 89797 C226 I F V I T V E C S E R G S D G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 I424 A Q M L E R I I V T E Q E N E
Frog Xenopus laevis P28025 1060 119314 T445 K E L E E C T T I L Q C K E K
Zebra Danio Brachydanio rerio NP_775368 955 106984 K385 T E E I E R L K R D L A A T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 E456 Q E L K K T E E N L L N T K G
Honey Bee Apis mellifera XP_623508 706 80766 F136 P R S L S H L F D E L R V L E
Nematode Worm Caenorhab. elegans P46873 699 78760 F129 A T T E N V K F L V H C S Y L
Sea Urchin Strong. purpuratus P46872 699 78679 G129 N S F A H I F G H I A K E Q E
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 H470 E L H N S Q L H L T A D L S E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 R445 D K Y V G Q V R E C S D L T T
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 L504 L Q S E K E K L I A I I Q N F
Red Bread Mold Neurospora crassa P48467 928 102392 S358 K A K T Q I T S F E N Y I V N
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 20 100 N.A. 93.3 0 N.A. N.A. 0 40 13.3 N.A. 26.6 6.6 6.6 6.6
P-Site Similarity: 100 100 40 100 N.A. 93.3 20 N.A. N.A. 40 66.6 26.6 N.A. 46.6 13.3 20 26.6
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 0 N.A. N.A. 6.6 6.6 13.3
P-Site Similarity: 26.6 N.A. N.A. 33.3 33.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 0 6 0 0 6 0 0 12 12 6 6 0 0 % A
% Cys: 0 0 0 0 0 30 0 6 0 6 0 12 0 0 0 % C
% Asp: 6 0 0 30 0 0 0 0 30 6 0 12 0 6 0 % D
% Glu: 6 42 6 18 18 6 12 6 12 18 6 0 12 6 24 % E
% Phe: 0 6 6 0 0 0 6 12 6 0 0 0 0 0 6 % F
% Gly: 6 0 0 0 6 0 0 6 0 0 6 6 0 0 12 % G
% His: 0 0 6 0 6 6 0 6 6 0 6 0 0 0 0 % H
% Ile: 6 0 0 12 0 12 6 6 12 6 6 6 12 0 0 % I
% Lys: 12 6 6 6 18 0 36 6 0 0 0 6 30 6 6 % K
% Leu: 6 6 36 12 0 0 18 6 12 36 18 0 12 6 6 % L
% Met: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 30 0 0 6 6 0 0 0 6 0 6 30 0 18 6 % N
% Pro: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 6 12 0 0 30 12 0 0 0 0 30 6 6 6 30 % Q
% Arg: 0 6 0 0 0 18 0 12 6 0 6 6 0 0 6 % R
% Ser: 0 6 12 0 12 0 0 30 6 0 6 0 12 6 0 % S
% Thr: 6 6 6 6 6 6 12 6 0 12 0 6 6 36 6 % T
% Val: 0 0 12 6 0 12 6 0 6 6 0 0 6 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 0 0 0 0 0 0 0 6 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _