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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 7.88
Human Site: T1044 Identified Species: 10.83
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 T1044 E T T E H L V T K S R L P L R
Chimpanzee Pan troglodytes XP_507923 1056 119132 T1044 E T T E H L V T K S R L P L R
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 L844 L N E R E Q E L Q N L L E V I
Dog Lupus familis XP_534964 1334 149091 V1325 E E T T E H S V T R S R L P L
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 S1040 E A S D L S I S K S R L P L H
Rat Rattus norvegicus O55165 796 89797 L787 A S M A S A P L H P A T V V D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 R1188 T A A S L L V R D E E S Q E N
Frog Xenopus laevis P28025 1060 119314 L1049 M D E V D Q A L T K S K L P L
Zebra Danio Brachydanio rerio NP_775368 955 106984 R946 R K E Y M Y P R V L S R P R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 L1044 S S S L S R S L T P S K T S P
Honey Bee Apis mellifera XP_623508 706 80766 I697 N E P V S N N I L K E E A I D
Nematode Worm Caenorhab. elegans P46873 699 78760 P690 R A Q S A K R P P R L A S L N
Sea Urchin Strong. purpuratus P46872 699 78679 M690 G K K K Q A S M A S S I D A L
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 A1046 N G D I K H V A A A F E A A Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 G1031 L L H N A N L G P F L V M M V
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 K1094 F T T E P I L K G E E T E N N
Red Bread Mold Neurospora crassa P48467 928 102392 K919 Q Q N P P E N K R S S W F F Q
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 6.6 13.3 N.A. 46.6 0 N.A. N.A. 13.3 0 6.6 N.A. 0 0 6.6 6.6
P-Site Similarity: 100 100 26.6 13.3 N.A. 73.3 13.3 N.A. N.A. 13.3 0 6.6 N.A. 13.3 6.6 6.6 20
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 6.6 N.A. N.A. 0 20 6.6
P-Site Similarity: 20 N.A. N.A. 20 33.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 18 6 6 12 12 6 6 12 6 6 6 12 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 6 6 6 6 0 0 0 6 0 0 0 6 0 12 % D
% Glu: 24 12 18 18 12 6 6 0 0 12 18 12 12 6 0 % E
% Phe: 6 0 0 0 0 0 0 0 0 6 6 0 6 6 0 % F
% Gly: 6 6 0 0 0 0 0 6 6 0 0 0 0 0 0 % G
% His: 0 0 6 0 12 12 0 0 6 0 0 0 0 0 6 % H
% Ile: 0 0 0 6 0 6 6 6 0 0 0 6 0 6 6 % I
% Lys: 0 12 6 6 6 6 0 12 18 12 0 12 0 0 0 % K
% Leu: 12 6 0 6 12 18 12 24 6 6 18 24 12 24 18 % L
% Met: 6 0 6 0 6 0 0 6 0 0 0 0 6 6 0 % M
% Asn: 12 6 6 6 0 12 12 0 0 6 0 0 0 6 18 % N
% Pro: 0 0 6 6 12 0 12 6 12 12 0 0 24 12 6 % P
% Gln: 6 6 6 0 6 12 0 0 6 0 0 0 6 0 12 % Q
% Arg: 12 0 0 6 0 6 6 12 6 12 18 12 0 6 12 % R
% Ser: 6 12 12 12 18 6 18 6 0 30 36 6 6 6 6 % S
% Thr: 6 18 24 6 0 0 0 12 18 0 0 12 6 0 0 % T
% Val: 0 0 0 12 0 0 24 6 6 0 0 6 6 12 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % W
% Tyr: 0 0 0 6 0 6 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _