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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 15.45
Human Site: T482 Identified Species: 21.25
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 T482 L V K E E Y I T S A L E S T E
Chimpanzee Pan troglodytes XP_507923 1056 119132 T482 L V K E E Y I T S A L E S T E
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 E313 T P H V P Y R E S K L T R I L
Dog Lupus familis XP_534964 1334 149091 T764 L V E E E Y I T S A L E I T E
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 S481 L V K E E Y V S S A L E R T E
Rat Rattus norvegicus O55165 796 89797 A256 G S E R Q N K A G P N T P G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 L454 K L D L Q K L L E T V E D E E
Frog Xenopus laevis P28025 1060 119314 V475 L A Q E S F V V S A F E T T E
Zebra Danio Brachydanio rerio NP_775368 955 106984 E415 N G K I V S Q E E Q I T E Y T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 V486 Y K E K K E L V A S H M K T E
Honey Bee Apis mellifera XP_623508 706 80766 S166 E E I F D L L S S S D D A A K
Nematode Worm Caenorhab. elegans P46873 699 78760 E159 K Q K L E I K E Q P D R G V Y
Sea Urchin Strong. purpuratus P46872 699 78679 G159 E E V K D L L G K D Q Q H R L
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 H500 L V D L E E K H R Q A N I T I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 L475 L A S T N E E L K K S Q Y A M
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 N534 H T N L E L M N E V I Q Q R D
Red Bread Mold Neurospora crassa P48467 928 102392 L388 K E K W V P P L E L A I T P S
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 20 86.6 N.A. 80 0 N.A. N.A. 13.3 46.6 6.6 N.A. 13.3 6.6 13.3 0
P-Site Similarity: 100 100 20 93.3 N.A. 93.3 13.3 N.A. N.A. 40 73.3 13.3 N.A. 53.3 53.3 13.3 26.6
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 26.6 N.A. N.A. 6.6 6.6 6.6
P-Site Similarity: 26.6 N.A. N.A. 13.3 33.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 0 0 6 6 30 12 0 6 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 12 0 12 0 0 0 0 6 12 6 6 0 6 % D
% Glu: 12 18 18 30 42 18 6 18 24 0 0 36 6 6 42 % E
% Phe: 0 0 0 6 0 6 0 0 0 0 6 0 0 0 0 % F
% Gly: 6 6 0 0 0 0 0 6 6 0 0 0 6 6 6 % G
% His: 6 0 6 0 0 0 0 6 0 0 6 0 6 0 0 % H
% Ile: 0 0 6 6 0 6 18 0 0 0 12 6 12 6 6 % I
% Lys: 18 6 36 12 6 6 18 0 12 12 0 0 6 0 6 % K
% Leu: 42 6 0 24 0 18 24 18 0 6 30 0 0 0 12 % L
% Met: 0 0 0 0 0 0 6 0 0 0 0 6 0 0 6 % M
% Asn: 6 0 6 0 6 6 0 6 0 0 6 6 0 0 0 % N
% Pro: 0 6 0 0 6 6 6 0 0 12 0 0 6 6 0 % P
% Gln: 0 6 6 0 12 0 6 0 6 12 6 18 6 0 0 % Q
% Arg: 0 0 0 6 0 0 6 0 6 0 0 6 12 12 0 % R
% Ser: 0 6 6 0 6 6 0 12 42 12 6 0 12 0 6 % S
% Thr: 6 6 0 6 0 0 0 18 0 6 0 18 12 42 6 % T
% Val: 0 30 6 6 12 0 12 12 0 6 6 0 0 6 0 % V
% Trp: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 0 0 0 0 30 0 0 0 0 0 0 6 6 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _