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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF11
All Species:
17.88
Human Site:
T643
Identified Species:
24.58
UniProt:
P52732
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52732
NP_004514.2
1056
119159
T643
L
E
M
I
L
S
P
T
V
V
S
I
L
K
I
Chimpanzee
Pan troglodytes
XP_507923
1056
119132
T643
L
E
M
I
L
S
P
T
V
V
S
I
L
K
I
Rhesus Macaque
Macaca mulatta
XP_001087644
853
96218
T464
K
T
Q
E
L
E
T
T
Q
K
H
L
Q
E
T
Dog
Lupus familis
XP_534964
1334
149091
T925
L
E
T
V
L
S
P
T
V
V
S
I
L
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9P6
1052
118008
S642
L
K
T
I
V
A
P
S
V
V
S
I
L
N
I
Rat
Rattus norvegicus
O55165
796
89797
R407
G
M
L
G
K
R
P
R
R
K
S
S
R
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90640
1225
138905
R607
L
S
E
R
R
R
K
R
L
Q
E
L
E
G
Q
Frog
Xenopus laevis
P28025
1060
119314
V636
L
R
S
D
L
L
P
V
V
T
A
V
L
D
L
Zebra Danio
Brachydanio rerio
NP_775368
955
106984
V566
I
D
Y
Y
R
S
S
V
G
E
L
L
N
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46863
1066
121145
T646
L
M
S
K
E
I
Q
T
N
L
Q
V
I
E
E
Honey Bee
Apis mellifera
XP_623508
706
80766
G317
R
L
L
Q
E
S
L
G
G
R
T
R
T
S
I
Nematode Worm
Caenorhab. elegans
P46873
699
78760
N310
C
V
S
P
S
S
D
N
Y
D
E
T
L
S
T
Sea Urchin
Strong. purpuratus
P46872
699
78679
N310
L
Q
D
S
L
G
G
N
A
K
T
V
M
C
A
Poplar Tree
Populus trichocarpa
XP_002314206
1066
119757
V653
F
G
S
L
N
S
E
V
S
K
H
S
H
A
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P82266
1056
119250
T628
L
E
E
V
S
A
L
T
T
S
S
A
C
S
I
Baker's Yeast
Sacchar. cerevisiae
P28742
1111
125776
N689
S
I
N
E
I
S
Q
N
C
T
T
N
L
N
S
Red Bread Mold
Neurospora crassa
P48467
928
102392
K539
K
Q
Q
M
L
D
M
K
M
S
A
K
E
T
S
Conservation
Percent
Protein Identity:
100
99.8
77.5
69.3
N.A.
79.7
23.3
N.A.
N.A.
25.3
56.2
47.7
N.A.
33.5
37.1
27.4
29.2
Protein Similarity:
100
99.9
79
73.8
N.A.
89
40.4
N.A.
N.A.
43.5
72.7
63.9
N.A.
55.4
52
42.5
42.8
P-Site Identity:
100
100
13.3
86.6
N.A.
60
13.3
N.A.
N.A.
6.6
33.3
6.6
N.A.
13.3
13.3
13.3
13.3
P-Site Similarity:
100
100
26.6
93.3
N.A.
86.6
26.6
N.A.
N.A.
20
53.3
26.6
N.A.
40
26.6
13.3
40
Percent
Protein Identity:
32.9
N.A.
N.A.
31.9
27.2
27.5
Protein Similarity:
52.3
N.A.
N.A.
51.5
48.6
45.5
P-Site Identity:
6.6
N.A.
N.A.
33.3
13.3
6.6
P-Site Similarity:
20
N.A.
N.A.
46.6
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
0
6
0
12
6
0
6
6
% A
% Cys:
6
0
0
0
0
0
0
0
6
0
0
0
6
6
0
% C
% Asp:
0
6
6
6
0
6
6
0
0
6
0
0
0
6
0
% D
% Glu:
0
24
12
12
12
6
6
0
0
6
12
0
12
12
6
% E
% Phe:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
6
6
0
6
0
6
6
6
12
0
0
0
0
6
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
6
0
0
% H
% Ile:
6
6
0
18
6
6
0
0
0
0
0
24
6
0
36
% I
% Lys:
12
6
0
6
6
0
6
6
0
24
0
6
0
18
6
% K
% Leu:
53
6
12
6
42
6
12
0
6
6
6
18
42
0
6
% L
% Met:
0
12
12
6
0
0
6
0
6
0
0
0
6
0
0
% M
% Asn:
0
0
6
0
6
0
0
18
6
0
0
6
6
12
6
% N
% Pro:
0
0
0
6
0
0
36
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
12
6
0
0
12
0
6
6
6
0
6
0
6
% Q
% Arg:
6
6
0
6
12
12
0
12
6
6
0
6
6
6
0
% R
% Ser:
6
6
24
6
12
48
6
6
6
12
36
12
0
18
12
% S
% Thr:
0
6
12
0
0
0
6
36
6
12
18
6
6
12
12
% T
% Val:
0
6
0
12
6
0
0
18
30
24
0
18
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
6
6
0
0
0
0
6
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _