Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 17.27
Human Site: T663 Identified Species: 23.75
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 T663 H I F K T S L T V A D K I E D
Chimpanzee Pan troglodytes XP_507923 1056 119132 T663 H I F K T S L T V A D K I E D
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 A484 K E E Y I T S A L E S T E E K
Dog Lupus familis XP_534964 1334 149091 T945 H I F K T S L T V A S K I E D
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 T662 H I F R A S S T V A E K V E D
Rat Rattus norvegicus O55165 796 89797 A427 P A G Y P E G A V I E A W V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 K627 K K L N E Q A K L L K L K E S
Frog Xenopus laevis P28025 1060 119314 I656 H C L Q N F L I V A D K I D S
Zebra Danio Brachydanio rerio NP_775368 955 106984 E586 E T L G A V C E S Y S S I K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 Q666 K A M L D S M Q E K F A T I I
Honey Bee Apis mellifera XP_623508 706 80766 E337 P A S I N L E E T L S T L D Y
Nematode Worm Caenorhab. elegans P46873 699 78760 K330 R A K N I K N K P T I N E D P
Sea Urchin Strong. purpuratus P46872 699 78679 I330 E Y N Y D E T I S T L R Y A N
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 A673 R I A S E A D A L I N D L Q S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 S648 S G D E T T S S L F D E L Q S
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 S709 E N Q Q S G S S K L I K E Q D
Red Bread Mold Neurospora crassa P48467 928 102392 K559 K E K K K A E K M A K M M A G
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 6.6 93.3 N.A. 66.6 6.6 N.A. N.A. 6.6 46.6 6.6 N.A. 6.6 0 0 0
P-Site Similarity: 100 100 20 93.3 N.A. 86.6 13.3 N.A. N.A. 13.3 60 13.3 N.A. 13.3 13.3 6.6 13.3
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 6.6 N.A. N.A. 13.3 13.3 13.3
P-Site Similarity: 40 N.A. N.A. 60 40 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 6 0 12 12 6 18 0 36 0 12 0 12 6 % A
% Cys: 0 6 0 0 0 0 6 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 6 0 12 0 6 0 0 0 24 6 0 18 30 % D
% Glu: 18 12 6 6 12 12 12 12 6 6 12 6 18 36 0 % E
% Phe: 0 0 24 0 0 6 0 0 0 6 6 0 0 0 0 % F
% Gly: 0 6 6 6 0 6 6 0 0 0 0 0 0 0 12 % G
% His: 30 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 30 0 6 12 0 0 12 0 12 12 0 30 6 6 % I
% Lys: 24 6 12 24 6 6 0 18 6 6 12 36 6 6 6 % K
% Leu: 0 0 18 6 0 6 24 0 24 18 6 6 18 0 0 % L
% Met: 0 0 6 0 0 0 6 0 6 0 0 6 6 0 0 % M
% Asn: 0 6 6 12 12 0 6 0 0 0 6 6 0 0 6 % N
% Pro: 12 0 0 0 6 0 0 0 6 0 0 0 0 0 6 % P
% Gln: 0 0 6 12 0 6 0 6 0 0 0 0 0 18 0 % Q
% Arg: 12 0 0 6 0 0 0 0 0 0 0 6 0 0 0 % R
% Ser: 6 0 6 6 6 30 24 12 12 0 24 6 0 0 24 % S
% Thr: 0 6 0 0 24 12 6 24 6 12 0 12 6 0 0 % T
% Val: 0 0 0 0 0 6 0 0 36 0 0 0 6 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % W
% Tyr: 0 6 0 18 0 0 0 0 0 6 0 0 6 0 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _