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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHN2 All Species: 14.55
Human Site: T183 Identified Species: 32
UniProt: P52757 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52757 NP_001035025.1 468 53924 T183 E P R K T N V T H E E H T A V
Chimpanzee Pan troglodytes XP_527708 780 87105 T495 E P R K T N V T H E E H T A V
Rhesus Macaque Macaca mulatta XP_001088070 468 53835 T183 E P R K T N V T H E E H T A V
Dog Lupus familis XP_532501 415 47910 F164 N Y E K T H N F K V H T F R G
Cat Felis silvestris
Mouse Mus musculus Q91V57 459 53175 A173 E T H D E K E A T G Q D G V S
Rat Rattus norvegicus Q03070 295 33819 F44 N Y E K T H N F K V H T F R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511818 490 55727 T205 E S R K T S V T S E E H A T M
Chicken Gallus gallus Q5ZMM3 475 54591 N187 D W F H A I K N A I D R L P K
Frog Xenopus laevis NP_001080335 459 52931 C173 E A H V E K D C P V E D G L S
Zebra Danio Brachydanio rerio NP_998165 459 52828 S173 D L P D G K H S P A E D S G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780071 824 93874 S519 P Q S M P D H S P P G P P T K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.8 99.3 86.3 N.A. 70.9 60 N.A. 83.8 21.8 70.9 72.2 N.A. N.A. N.A. N.A. 26.8
Protein Similarity: 100 60 100 87.8 N.A. 83.9 62.1 N.A. 88.7 44.2 83.3 83.7 N.A. N.A. N.A. N.A. 39.8
P-Site Identity: 100 100 100 13.3 N.A. 6.6 13.3 N.A. 60 0 13.3 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 20 N.A. 13.3 20 N.A. 73.3 13.3 13.3 33.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 0 0 10 10 10 0 0 10 28 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 19 0 0 19 0 10 10 0 0 0 10 28 0 0 0 % D
% Glu: 55 0 19 0 19 0 10 0 0 37 55 0 0 0 0 % E
% Phe: 0 0 10 0 0 0 0 19 0 0 0 0 19 0 0 % F
% Gly: 0 0 0 0 10 0 0 0 0 10 10 0 19 10 19 % G
% His: 0 0 19 10 0 19 19 0 28 0 19 37 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 55 0 28 10 0 19 0 0 0 0 0 19 % K
% Leu: 0 10 0 0 0 0 0 0 0 0 0 0 10 10 10 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 19 0 0 0 0 28 19 10 0 0 0 0 0 0 0 % N
% Pro: 10 28 10 0 10 0 0 0 28 10 0 10 10 10 0 % P
% Gln: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 37 0 0 0 0 0 0 0 0 10 0 19 0 % R
% Ser: 0 10 10 0 0 10 0 19 10 0 0 0 10 0 19 % S
% Thr: 0 10 0 0 55 0 0 37 10 0 0 19 28 19 0 % T
% Val: 0 0 0 10 0 0 37 0 0 28 0 0 0 10 28 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _