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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRSP12
All Species:
15.2
Human Site:
S136
Identified Species:
27.86
UniProt:
P52758
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52758
NP_005827.1
137
14494
S136
Q
G
P
L
T
T
A
S
L
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001149111
137
14461
S136
Q
G
P
L
T
T
A
S
L
_
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001090561
137
14467
S136
Q
G
P
L
T
T
A
S
L
_
_
_
_
_
_
Dog
Lupus familis
XP_532278
137
14300
S136
L
G
P
L
T
T
A
S
L
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P52760
135
14237
A125
G
S
R
V
E
I
E
A
I
A
V
Q
G
P
F
Rat
Rattus norvegicus
P52759
137
14285
G136
Q
G
P
F
T
T
A
G
L
_
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506391
133
14061
A125
G
G
R
V
E
I
E
A
I
A
V
T
K
A
R
Chicken
Gallus gallus
XP_001234689
295
31154
P292
Q
G
P
I
Q
N
V
P
A
S
L
_
_
_
_
Frog
Xenopus laevis
NP_001084732
139
14609
S136
L
G
P
I
T
E
I
S
P
A
L
_
_
_
_
Zebra Danio
Brachydanio rerio
NP_001012315
135
14177
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10121
171
18025
K170
A
G
E
I
E
E
V
K
N
_
_
_
_
_
_
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_188674
187
19797
C183
N
A
K
I
E
I
E
C
I
A
T
L
_
_
_
Baker's Yeast
Sacchar. cerevisiae
P40185
145
15890
E143
E
M
E
V
I
A
V
E
K
N
_
_
_
_
_
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
95.6
91.9
N.A.
80.2
87.5
N.A.
83.2
35.5
75.5
71.5
N.A.
N.A.
N.A.
50.8
N.A.
Protein Similarity:
100
100
97.8
97
N.A.
89
93.4
N.A.
91.2
42.7
92.8
86.1
N.A.
N.A.
N.A.
61.9
N.A.
P-Site Identity:
100
100
100
88.8
N.A.
0
77.7
N.A.
6.6
27.2
36.3
0
N.A.
N.A.
N.A.
11.1
N.A.
P-Site Similarity:
100
100
100
88.8
N.A.
26.6
77.7
N.A.
26.6
36.3
45.4
0
N.A.
N.A.
N.A.
22.2
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.1
33.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
55.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
16.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
8
39
16
8
31
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
16
0
31
16
24
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
16
70
0
0
0
0
0
8
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
31
8
24
8
0
24
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
8
8
0
0
0
8
0
0
% K
% Leu:
16
0
0
31
0
0
0
0
39
0
16
8
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
0
8
8
0
0
0
0
0
% N
% Pro:
0
0
54
0
0
0
0
8
8
0
0
0
0
8
0
% P
% Gln:
39
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
8
0
0
0
0
0
39
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
47
39
0
0
0
0
8
8
0
0
0
% T
% Val:
0
0
0
24
0
0
24
0
0
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
47
54
70
77
77
77
% _