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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRSP12
All Species:
33.94
Human Site:
Y110
Identified Species:
62.22
UniProt:
P52758
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52758
NP_005827.1
137
14494
Y110
N
F
P
A
R
A
A
Y
Q
V
A
A
L
P
K
Chimpanzee
Pan troglodytes
XP_001149111
137
14461
Y110
N
F
P
A
R
A
A
Y
Q
V
A
A
L
P
K
Rhesus Macaque
Macaca mulatta
XP_001090561
137
14467
Y110
N
F
P
A
R
A
A
Y
Q
V
V
A
L
S
K
Dog
Lupus familis
XP_532278
137
14300
Y110
S
F
P
A
R
A
A
Y
Q
V
A
A
L
P
K
Cat
Felis silvestris
Mouse
Mus musculus
P52760
135
14237
Y99
V
N
E
I
Y
K
T
Y
F
Q
G
S
L
P
A
Rat
Rattus norvegicus
P52759
137
14285
Y110
N
L
P
A
R
A
A
Y
Q
V
A
A
L
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506391
133
14061
Y99
V
N
E
I
Y
K
Q
Y
F
K
S
S
F
P
A
Chicken
Gallus gallus
XP_001234689
295
31154
F266
N
C
P
S
R
V
S
F
Q
V
A
A
L
P
K
Frog
Xenopus laevis
NP_001084732
139
14609
Y110
N
F
P
A
R
A
A
Y
Q
V
A
A
L
P
R
Zebra Danio
Brachydanio rerio
NP_001012315
135
14177
Y109
N
F
P
A
R
A
A
Y
Q
V
V
A
L
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10121
171
18025
Y144
P
Y
P
A
R
A
A
Y
Q
V
A
A
L
P
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_188674
187
19797
Y157
V
N
E
I
Y
A
K
Y
F
P
A
P
S
P
A
Baker's Yeast
Sacchar. cerevisiae
P40185
145
15890
H117
Y
A
K
H
F
H
T
H
K
P
A
R
S
C
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
95.6
91.9
N.A.
80.2
87.5
N.A.
83.2
35.5
75.5
71.5
N.A.
N.A.
N.A.
50.8
N.A.
Protein Similarity:
100
100
97.8
97
N.A.
89
93.4
N.A.
91.2
42.7
92.8
86.1
N.A.
N.A.
N.A.
61.9
N.A.
P-Site Identity:
100
100
86.6
93.3
N.A.
20
93.3
N.A.
13.3
66.6
93.3
86.6
N.A.
N.A.
N.A.
86.6
N.A.
P-Site Similarity:
100
100
86.6
100
N.A.
26.6
93.3
N.A.
26.6
86.6
100
93.3
N.A.
N.A.
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.1
33.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
55.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
62
0
70
62
0
0
0
70
70
0
0
24
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
47
0
0
8
0
0
8
24
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
8
0
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
24
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
16
8
0
8
8
0
0
0
0
54
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
0
0
77
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
54
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
70
0
0
0
0
0
0
16
0
8
0
85
0
% P
% Gln:
0
0
0
0
0
0
8
0
70
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
70
0
0
0
0
0
0
8
0
0
16
% R
% Ser:
8
0
0
8
0
0
8
0
0
0
8
16
16
8
0
% S
% Thr:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% T
% Val:
24
0
0
0
0
8
0
0
0
70
16
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
24
0
0
85
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _