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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMS
All Species:
26.36
Human Site:
S184
Identified Species:
52.73
UniProt:
P52788
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52788
NP_004586.2
366
41268
S184
Y
T
R
A
I
M
G
S
G
K
E
D
Y
T
G
Chimpanzee
Pan troglodytes
XP_001142843
367
41364
S184
Y
T
R
A
I
M
G
S
G
K
E
D
Y
T
G
Rhesus Macaque
Macaca mulatta
XP_001086702
408
45991
S206
Y
T
R
A
I
M
G
S
G
K
E
D
Y
T
G
Dog
Lupus familis
XP_537978
270
30555
L101
S
G
K
D
V
L
I
L
G
G
G
D
G
G
I
Cat
Felis silvestris
Mouse
Mus musculus
P97355
366
41295
S184
Y
T
R
A
I
M
G
S
G
K
E
D
Y
T
G
Rat
Rattus norvegicus
XP_001062228
366
41276
N184
Y
T
R
A
I
M
G
N
G
K
E
D
Y
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513704
522
59135
S339
Y
T
Q
A
I
M
G
S
G
K
E
D
Y
A
G
Chicken
Gallus gallus
NP_001025974
367
41879
S184
Y
T
R
A
I
M
G
S
G
K
E
D
Y
T
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571831
360
40601
S181
Y
T
Q
A
I
M
G
S
G
K
E
H
Y
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_729798
367
42477
R189
Y
T
E
T
L
M
C
R
G
V
E
N
Y
E
G
Honey Bee
Apis mellifera
XP_393567
366
41561
R188
Y
T
E
T
L
M
Q
R
G
K
E
N
Y
T
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789223
457
51774
N193
Y
T
Q
A
I
T
G
N
G
R
E
S
Y
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
86.5
73.2
N.A.
96.1
96.9
N.A.
59.3
86.6
N.A.
69.6
N.A.
43
42.6
N.A.
39.8
Protein Similarity:
100
99.7
87.7
73.7
N.A.
98
98.6
N.A.
64.5
92.3
N.A.
84.4
N.A.
62.1
62.5
N.A.
55.5
P-Site Identity:
100
100
100
13.3
N.A.
100
93.3
N.A.
86.6
100
N.A.
80
N.A.
46.6
60
N.A.
66.6
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
93.3
100
N.A.
86.6
N.A.
60
73.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
75
0
0
0
0
0
0
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
67
0
0
0
% D
% Glu:
0
0
17
0
0
0
0
0
0
0
92
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
75
0
100
9
9
0
9
9
92
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
75
0
9
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
9
0
0
0
0
0
0
75
0
0
0
0
0
% K
% Leu:
0
0
0
0
17
9
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
84
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
17
0
0
0
17
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
25
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
50
0
0
0
0
17
0
9
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
0
59
0
0
0
9
0
0
0
% S
% Thr:
0
92
0
17
0
9
0
0
0
0
0
0
0
67
0
% T
% Val:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
92
0
0
0
0
0
0
0
0
0
0
0
92
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _