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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMS
All Species:
28.18
Human Site:
S285
Identified Species:
56.36
UniProt:
P52788
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52788
NP_004586.2
366
41268
S285
T
A
V
P
I
S
T
S
P
E
E
D
S
T
W
Chimpanzee
Pan troglodytes
XP_001142843
367
41364
S286
T
A
V
P
I
S
T
S
P
E
E
D
S
T
W
Rhesus Macaque
Macaca mulatta
XP_001086702
408
45991
S307
T
A
V
P
I
S
T
S
P
E
E
D
S
T
W
Dog
Lupus familis
XP_537978
270
30555
P190
A
V
P
I
S
T
S
P
E
E
D
S
T
W
E
Cat
Felis silvestris
Mouse
Mus musculus
P97355
366
41295
S285
T
A
V
P
I
S
T
S
P
E
E
D
S
T
W
Rat
Rattus norvegicus
XP_001062228
366
41276
S285
T
A
V
P
I
S
T
S
P
E
E
D
S
T
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513704
522
59135
S440
T
A
V
P
I
S
T
S
P
E
E
D
S
T
W
Chicken
Gallus gallus
NP_001025974
367
41879
S285
T
A
V
P
I
S
T
S
P
E
E
D
S
T
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571831
360
40601
P278
I
N
D
L
T
A
V
P
I
S
T
A
P
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_729798
367
42477
I285
V
F
G
D
L
T
D
I
P
I
T
D
A
P
E
Honey Bee
Apis mellifera
XP_393567
366
41561
T282
D
Y
V
F
G
D
L
T
D
I
P
I
S
P
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789223
457
51774
E294
T
A
I
P
I
T
T
E
P
R
G
S
Q
W
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
86.5
73.2
N.A.
96.1
96.9
N.A.
59.3
86.6
N.A.
69.6
N.A.
43
42.6
N.A.
39.8
Protein Similarity:
100
99.7
87.7
73.7
N.A.
98
98.6
N.A.
64.5
92.3
N.A.
84.4
N.A.
62.1
62.5
N.A.
55.5
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
100
100
N.A.
0
N.A.
13.3
13.3
N.A.
40
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
100
100
N.A.
6.6
N.A.
33.3
20
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
67
0
0
0
9
0
0
0
0
0
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
9
0
9
9
0
9
0
9
67
0
0
9
% D
% Glu:
0
0
0
0
0
0
0
9
9
67
59
0
0
9
25
% E
% Phe:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
9
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
9
9
67
0
0
9
9
17
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
9
0
9
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
67
0
0
0
17
75
0
9
0
9
17
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
0
0
0
9
59
9
59
0
9
0
17
67
0
0
% S
% Thr:
67
0
0
0
9
25
67
9
0
0
17
0
9
59
9
% T
% Val:
9
9
67
0
0
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
59
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _