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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMS
All Species:
39.7
Human Site:
Y123
Identified Species:
79.39
UniProt:
P52788
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52788
NP_004586.2
366
41268
Y123
R
G
G
A
I
D
R
Y
W
P
T
A
D
G
R
Chimpanzee
Pan troglodytes
XP_001142843
367
41364
Y123
R
G
G
A
I
D
R
Y
W
P
T
A
D
G
R
Rhesus Macaque
Macaca mulatta
XP_001086702
408
45991
Y145
R
G
G
A
I
D
R
Y
W
P
T
A
D
G
R
Dog
Lupus familis
XP_537978
270
30555
I40
G
R
L
V
E
Y
D
I
D
E
V
V
Y
D
E
Cat
Felis silvestris
Mouse
Mus musculus
P97355
366
41295
Y123
R
G
G
A
I
D
R
Y
W
P
T
A
D
G
R
Rat
Rattus norvegicus
XP_001062228
366
41276
Y123
R
G
G
A
I
D
R
Y
W
P
T
A
D
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513704
522
59135
Y278
R
G
G
A
V
D
R
Y
W
P
T
A
D
G
R
Chicken
Gallus gallus
NP_001025974
367
41879
Y123
R
G
G
V
I
D
R
Y
W
P
T
A
D
G
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571831
360
40601
Y120
R
G
S
D
V
D
R
Y
W
P
T
A
D
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_729798
367
42477
Y128
R
G
G
Y
I
D
I
Y
M
T
S
S
D
E
R
Honey Bee
Apis mellifera
XP_393567
366
41561
Y127
R
G
T
I
Y
D
L
Y
L
T
L
S
D
D
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789223
457
51774
Y132
R
G
A
A
V
D
R
Y
I
P
T
A
D
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
86.5
73.2
N.A.
96.1
96.9
N.A.
59.3
86.6
N.A.
69.6
N.A.
43
42.6
N.A.
39.8
Protein Similarity:
100
99.7
87.7
73.7
N.A.
98
98.6
N.A.
64.5
92.3
N.A.
84.4
N.A.
62.1
62.5
N.A.
55.5
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
93.3
93.3
N.A.
80
N.A.
53.3
40
N.A.
73.3
P-Site Similarity:
100
100
100
0
N.A.
100
100
N.A.
100
93.3
N.A.
86.6
N.A.
66.6
46.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
59
0
0
0
0
0
0
0
75
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
92
9
0
9
0
0
0
92
17
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
9
0
0
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
92
67
0
0
0
0
0
0
0
0
0
0
67
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
59
0
9
9
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
0
0
9
0
9
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
75
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
92
9
0
0
0
0
75
0
0
0
0
0
0
9
92
% R
% Ser:
0
0
9
0
0
0
0
0
0
0
9
17
0
0
0
% S
% Thr:
0
0
9
0
0
0
0
0
0
17
75
0
0
0
0
% T
% Val:
0
0
0
17
25
0
0
0
0
0
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
9
9
0
92
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _