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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMS
All Species:
30.61
Human Site:
Y272
Identified Species:
61.21
UniProt:
P52788
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52788
NP_004586.2
366
41268
Y272
K
E
G
R
E
F
D
Y
V
I
N
D
L
T
A
Chimpanzee
Pan troglodytes
XP_001142843
367
41364
Y273
K
E
G
R
E
F
D
Y
V
I
N
D
L
T
A
Rhesus Macaque
Macaca mulatta
XP_001086702
408
45991
Y294
K
E
G
R
E
F
D
Y
V
I
N
D
L
T
A
Dog
Lupus familis
XP_537978
270
30555
V177
E
G
R
E
F
D
Y
V
I
N
D
L
T
A
V
Cat
Felis silvestris
Mouse
Mus musculus
P97355
366
41295
Y272
K
E
G
R
E
F
D
Y
V
I
N
D
L
T
A
Rat
Rattus norvegicus
XP_001062228
366
41276
Y272
K
E
G
R
E
F
D
Y
V
I
N
D
L
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513704
522
59135
Y427
K
E
G
R
L
F
D
Y
V
I
N
D
L
T
A
Chicken
Gallus gallus
NP_001025974
367
41879
Y272
K
E
G
R
M
F
D
Y
V
I
N
D
L
T
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571831
360
40601
R265
K
K
F
A
E
Q
G
R
T
F
D
Y
V
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_729798
367
42477
G272
L
K
K
F
I
A
E
G
R
K
F
D
Y
V
F
Honey Bee
Apis mellifera
XP_393567
366
41561
E269
K
T
L
A
H
M
I
E
E
G
R
Q
F
D
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789223
457
51774
Y281
A
D
G
K
M
F
D
Y
I
I
N
D
L
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
86.5
73.2
N.A.
96.1
96.9
N.A.
59.3
86.6
N.A.
69.6
N.A.
43
42.6
N.A.
39.8
Protein Similarity:
100
99.7
87.7
73.7
N.A.
98
98.6
N.A.
64.5
92.3
N.A.
84.4
N.A.
62.1
62.5
N.A.
55.5
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
93.3
93.3
N.A.
13.3
N.A.
6.6
6.6
N.A.
66.6
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
93.3
93.3
N.A.
33.3
N.A.
20
6.6
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
17
0
9
0
0
0
0
0
0
0
9
67
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
9
67
0
0
0
17
75
0
9
0
% D
% Glu:
9
59
0
9
50
0
9
9
9
0
0
0
0
0
0
% E
% Phe:
0
0
9
9
9
67
0
0
0
9
9
0
9
0
9
% F
% Gly:
0
9
67
0
0
0
9
9
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
9
0
17
67
0
0
0
9
0
% I
% Lys:
75
17
9
9
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
9
0
9
0
9
0
0
0
0
0
0
9
67
0
0
% L
% Met:
0
0
0
0
17
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
67
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
9
59
0
0
0
9
9
0
9
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
9
0
0
0
0
0
0
9
0
0
0
9
67
0
% T
% Val:
0
0
0
0
0
0
0
9
59
0
0
0
9
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
67
0
0
0
9
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _