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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HK2
All Species:
36.36
Human Site:
Y301
Identified Species:
88.89
UniProt:
P52789
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52789
NP_000180.2
917
102380
Y301
E
K
M
I
S
G
M
Y
M
G
E
L
V
R
L
Chimpanzee
Pan troglodytes
XP_001162535
917
102319
Y301
E
K
M
I
S
G
M
Y
M
G
E
L
V
R
L
Rhesus Macaque
Macaca mulatta
XP_001111706
917
102287
Y301
E
K
M
I
S
G
M
Y
M
G
E
L
V
R
L
Dog
Lupus familis
XP_532991
909
101134
Y293
E
K
M
I
S
G
M
Y
M
G
E
L
V
R
L
Cat
Felis silvestris
Mouse
Mus musculus
O08528
917
102517
Y301
E
K
M
I
S
G
M
Y
M
G
E
L
V
R
L
Rat
Rattus norvegicus
P27881
917
102526
Y301
E
K
M
I
S
G
M
Y
M
G
E
L
V
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989543
916
102399
Y301
E
K
M
I
S
G
M
Y
M
G
E
L
V
R
L
Frog
Xenopus laevis
NP_001096656
916
102431
Y301
E
K
M
V
S
G
M
Y
M
G
E
L
V
R
L
Zebra Danio
Brachydanio rerio
NP_998231
919
102145
Y301
E
K
M
I
S
G
M
Y
M
G
E
L
V
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NFT7
486
53467
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
93.5
N.A.
94.2
94.4
N.A.
N.A.
85.9
74.9
78.8
N.A.
26.1
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.3
95.9
N.A.
97.2
97.3
N.A.
N.A.
94.2
86.9
90.3
N.A.
37.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
100
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
90
0
0
0
0
0
0
0
0
0
90
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
90
0
0
0
90
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
80
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
90
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
90
0
0
90
% L
% Met:
0
0
90
0
0
0
90
0
90
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
90
0
% R
% Ser:
0
0
0
0
90
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
90
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
90
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _