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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HK3
All Species:
10.61
Human Site:
S17
Identified Species:
23.33
UniProt:
P52790
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52790
NP_002106.2
923
99025
S17
R
Q
G
E
E
T
L
S
C
S
E
E
G
L
P
Chimpanzee
Pan troglodytes
XP_518124
923
98989
S17
R
Q
G
E
E
A
L
S
C
S
E
E
G
L
P
Rhesus Macaque
Macaca mulatta
XP_001086179
923
98921
S17
R
Q
G
E
E
A
L
S
Y
P
E
E
G
L
P
Dog
Lupus familis
XP_546212
957
102956
G46
P
H
R
E
G
V
P
G
C
S
Q
E
G
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3TRM8
922
100082
V17
H
P
G
E
R
A
S
V
C
P
H
E
G
V
P
Rat
Rattus norvegicus
P27926
924
100236
S17
H
P
G
E
R
D
S
S
C
P
Q
E
G
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989543
916
102399
D17
F
F
T
E
L
N
H
D
Q
A
Q
K
V
D
K
Frog
Xenopus laevis
NP_001090603
913
99795
H17
H
N
D
Q
Q
A
R
H
E
Q
I
E
S
C
L
Zebra Danio
Brachydanio rerio
NP_998231
919
102145
H18
F
T
E
L
H
H
D
H
V
Q
K
V
D
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NFT7
486
53467
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FZG4
493
53861
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96
86.4
N.A.
85.4
85.3
N.A.
N.A.
55.6
55.7
55.1
N.A.
25.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
97.5
89.7
N.A.
90.4
90.8
N.A.
N.A.
72
72.3
71.1
N.A.
37.2
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
80
46.6
N.A.
40
46.6
N.A.
N.A.
6.6
6.6
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
80
53.3
N.A.
46.6
60
N.A.
N.A.
26.6
20
6.6
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
37
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
46
0
0
0
0
10
0
% C
% Asp:
0
0
10
0
0
10
10
10
0
0
0
0
10
10
0
% D
% Glu:
0
0
10
64
28
0
0
0
10
0
28
64
0
0
0
% E
% Phe:
19
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
46
0
10
0
0
10
0
0
0
0
55
0
0
% G
% His:
28
10
0
0
10
10
10
19
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
10
% K
% Leu:
0
0
0
10
10
0
28
0
0
0
0
0
0
37
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
19
0
0
0
0
10
0
0
28
0
0
0
0
55
% P
% Gln:
0
28
0
10
10
0
0
0
10
19
28
0
0
0
0
% Q
% Arg:
28
0
10
0
19
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
19
37
0
28
0
0
10
0
0
% S
% Thr:
0
10
10
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
10
10
0
0
10
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _