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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HK3 All Species: 14.24
Human Site: S30 Identified Species: 31.33
UniProt: P52790 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52790 NP_002106.2 923 99025 S30 L P G P S D S S E L V Q E C L
Chimpanzee Pan troglodytes XP_518124 923 98989 S30 L P G P S D S S E L V Q E C L
Rhesus Macaque Macaca mulatta XP_001086179 923 98921 S30 L P G P S D S S E L V Q E C L
Dog Lupus familis XP_546212 957 102956 S59 L P Y P S N S S E L V L E C L
Cat Felis silvestris
Mouse Mus musculus Q3TRM8 922 100082 L30 V P R P S G S L E L E C L Q Q
Rat Rattus norvegicus P27926 924 100236 L30 I P R P S G S L E L A Q E Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989543 916 102399 R30 D K Y L Y H M R L S E D T L Q
Frog Xenopus laevis NP_001090603 913 99795 S30 C L Q P F H L S Q A Q L L S V
Zebra Danio Brachydanio rerio NP_998231 919 102145 L31 K Y L Y H M R L S N E N L M D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NFT7 486 53467
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FZG4 493 53861
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96 86.4 N.A. 85.4 85.3 N.A. N.A. 55.6 55.7 55.1 N.A. 25.7 N.A. N.A. N.A.
Protein Similarity: 100 99.5 97.5 89.7 N.A. 90.4 90.8 N.A. N.A. 72 72.3 71.1 N.A. 37.2 N.A. N.A. N.A.
P-Site Identity: 100 100 100 80 N.A. 40 60 N.A. N.A. 0 13.3 0 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 46.6 66.6 N.A. N.A. 0 26.6 0 N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 33.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 10 0 37 0 % C
% Asp: 10 0 0 0 0 28 0 0 0 0 0 10 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 55 0 28 0 46 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 28 0 0 19 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 10 19 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 37 10 10 10 0 0 10 28 10 55 0 19 28 10 46 % L
% Met: 0 0 0 0 0 10 10 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 10 0 10 0 0 0 % N
% Pro: 0 55 0 64 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 10 0 10 37 0 10 19 % Q
% Arg: 0 0 19 0 0 0 10 10 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 55 0 55 46 10 10 0 0 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % T
% Val: 10 0 0 0 0 0 0 0 0 0 37 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 19 10 10 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _