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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HK3
All Species:
22.73
Human Site:
S598
Identified Species:
50
UniProt:
P52790
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52790
NP_002106.2
923
99025
S598
F
Q
Q
K
Q
G
L
S
G
Q
S
L
P
L
G
Chimpanzee
Pan troglodytes
XP_518124
923
98989
S598
F
Q
Q
K
Q
G
L
S
G
Q
S
L
P
L
G
Rhesus Macaque
Macaca mulatta
XP_001086179
923
98921
S598
F
Q
Q
K
Q
G
L
S
G
Q
S
L
P
L
G
Dog
Lupus familis
XP_546212
957
102956
S628
F
Q
Q
K
Q
G
L
S
G
Q
S
L
P
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3TRM8
922
100082
S597
F
Q
K
R
Q
G
L
S
G
Q
S
L
P
L
G
Rat
Rattus norvegicus
P27926
924
100236
S599
F
Q
K
R
Q
G
L
S
G
Q
S
L
P
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989543
916
102399
K592
F
L
E
Y
M
G
M
K
G
V
S
L
P
L
G
Frog
Xenopus laevis
NP_001090603
913
99795
R586
F
Q
S
E
N
N
L
R
G
R
R
L
P
L
G
Zebra Danio
Brachydanio rerio
NP_998231
919
102145
K594
F
L
E
Y
M
G
M
K
G
A
S
L
P
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NFT7
486
53467
I185
Q
Q
G
L
S
K
G
I
L
V
A
W
T
K
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FZG4
493
53861
G192
K
Q
T
S
I
D
S
G
T
L
S
K
W
T
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96
86.4
N.A.
85.4
85.3
N.A.
N.A.
55.6
55.7
55.1
N.A.
25.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
97.5
89.7
N.A.
90.4
90.8
N.A.
N.A.
72
72.3
71.1
N.A.
37.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
53.3
53.3
53.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
66.6
66.6
66.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
19
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
82
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
73
10
10
82
0
0
0
0
0
91
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
10
0
19
37
0
10
0
19
0
0
0
10
0
10
10
% K
% Leu:
0
19
0
10
0
0
64
0
10
10
0
82
0
82
0
% L
% Met:
0
0
0
0
19
0
19
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
82
0
0
% P
% Gln:
10
82
37
0
55
0
0
0
0
55
0
0
0
0
0
% Q
% Arg:
0
0
0
19
0
0
0
10
0
10
10
0
0
0
0
% R
% Ser:
0
0
10
10
10
0
10
55
0
0
82
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
0
10
0
0
0
10
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% W
% Tyr:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _