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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPL12
All Species:
28.18
Human Site:
S40
Identified Species:
47.69
UniProt:
P52815
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52815
NP_002940.2
198
21348
S40
A
V
R
H
M
R
S
S
G
H
Q
R
C
E
A
Chimpanzee
Pan troglodytes
XP_001163363
198
21340
S40
A
V
R
H
M
R
S
S
G
H
Q
R
C
E
A
Rhesus Macaque
Macaca mulatta
XP_001111712
198
21457
S40
A
M
R
H
M
R
S
S
G
H
R
R
C
E
A
Dog
Lupus familis
XP_850016
198
21413
S40
A
V
R
L
M
R
C
S
S
H
R
M
G
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB15
201
21690
S41
A
A
R
Q
L
R
S
S
S
H
R
R
S
E
A
Rat
Rattus norvegicus
NP_001025071
276
29423
S116
V
A
R
Q
L
R
S
S
S
H
R
R
S
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518289
336
34888
S142
A
V
R
P
M
R
G
S
G
R
R
R
G
E
A
Chicken
Gallus gallus
XP_001232214
194
20934
G32
A
A
R
P
L
G
T
G
R
A
R
R
R
S
E
Frog
Xenopus laevis
NP_001088496
190
20797
T32
T
V
R
L
L
R
T
T
S
E
L
R
N
L
S
Zebra Danio
Brachydanio rerio
NP_001017696
194
21202
S38
A
Q
R
T
L
K
T
S
S
V
S
A
V
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524742
182
19639
S31
A
A
P
A
A
A
V
S
G
A
E
K
L
V
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_499360
173
18420
A23
S
A
K
Y
S
Q
A
A
G
L
P
L
N
E
G
Sea Urchin
Strong. purpuratus
XP_790377
212
23073
N48
S
S
R
P
F
N
A
N
T
P
R
V
I
A
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53163
194
20631
R18
S
S
I
W
M
K
T
R
V
T
P
A
L
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.9
87.8
N.A.
85.5
63
N.A.
25
61.1
60.6
57
N.A.
35.3
N.A.
37.8
44.3
Protein Similarity:
100
99.4
97.9
90.4
N.A.
90.5
66.3
N.A.
33.3
71.2
73.2
70.7
N.A.
52.5
N.A.
56.5
54.2
P-Site Identity:
100
100
86.6
60
N.A.
60
53.3
N.A.
66.6
20
26.6
26.6
N.A.
20
N.A.
13.3
6.6
P-Site Similarity:
100
100
100
66.6
N.A.
73.3
66.6
N.A.
73.3
40
53.3
53.3
N.A.
33.3
N.A.
53.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
65
36
0
8
8
8
15
8
0
15
0
15
0
8
58
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
22
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
8
0
0
58
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
8
8
43
0
0
0
15
0
8
% G
% His:
0
0
0
22
0
0
0
0
0
43
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
0
8
0
0
15
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
0
0
15
36
0
0
0
0
8
8
8
15
8
0
% L
% Met:
0
8
0
0
43
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
0
0
0
0
15
0
0
% N
% Pro:
0
0
8
22
0
0
0
0
0
8
15
0
0
0
8
% P
% Gln:
0
8
0
15
0
8
0
0
0
0
15
0
0
0
0
% Q
% Arg:
0
0
79
0
0
58
0
8
8
8
50
58
8
0
0
% R
% Ser:
22
15
0
0
8
0
36
65
36
0
8
0
15
8
15
% S
% Thr:
8
0
0
8
0
0
29
8
8
8
0
0
0
0
0
% T
% Val:
8
36
0
0
0
0
8
0
8
8
0
8
8
8
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _