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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPL12
All Species:
42.73
Human Site:
T131
Identified Species:
72.31
UniProt:
P52815
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52815
NP_002940.2
198
21348
T131
A
K
E
R
T
H
F
T
V
R
L
T
E
A
K
Chimpanzee
Pan troglodytes
XP_001163363
198
21340
T131
A
K
E
R
T
H
F
T
V
R
L
T
E
A
K
Rhesus Macaque
Macaca mulatta
XP_001111712
198
21457
T131
A
K
E
R
T
H
F
T
V
R
L
T
E
A
N
Dog
Lupus familis
XP_850016
198
21413
T131
Q
K
E
R
T
H
F
T
V
R
L
T
E
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB15
201
21690
T134
Q
K
E
R
T
H
F
T
V
R
L
T
E
A
K
Rat
Rattus norvegicus
NP_001025071
276
29423
T209
Q
K
E
Q
T
H
F
T
V
R
L
T
E
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518289
336
34888
S278
P
R
E
R
S
T
S
S
T
A
N
E
A
E
S
Chicken
Gallus gallus
XP_001232214
194
20934
S127
K
K
E
K
T
H
F
S
V
R
L
T
E
L
K
Frog
Xenopus laevis
NP_001088496
190
20797
T123
K
K
E
K
T
N
F
T
V
K
L
T
E
V
N
Zebra Danio
Brachydanio rerio
NP_001017696
194
21202
T127
K
K
E
K
T
H
F
T
I
K
L
T
E
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524742
182
19639
K115
K
K
V
Q
T
S
F
K
V
K
L
V
K
F
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_499360
173
18420
T106
V
P
Q
K
M
T
F
T
V
K
L
T
K
F
D
Sea Urchin
Strong. purpuratus
XP_790377
212
23073
T145
A
P
E
K
T
Q
F
T
V
K
L
N
K
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53163
194
20631
T128
P
E
A
K
T
V
F
T
V
K
L
D
S
F
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.9
87.8
N.A.
85.5
63
N.A.
25
61.1
60.6
57
N.A.
35.3
N.A.
37.8
44.3
Protein Similarity:
100
99.4
97.9
90.4
N.A.
90.5
66.3
N.A.
33.3
71.2
73.2
70.7
N.A.
52.5
N.A.
56.5
54.2
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
86.6
N.A.
13.3
73.3
60
66.6
N.A.
33.3
N.A.
33.3
46.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
33.3
86.6
80
86.6
N.A.
53.3
N.A.
60
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
0
8
0
0
0
0
0
0
8
0
0
8
43
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
29
% D
% Glu:
0
8
79
0
0
0
0
0
0
0
0
8
65
8
0
% E
% Phe:
0
0
0
0
0
0
93
0
0
0
0
0
0
36
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
58
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
29
72
0
43
0
0
0
8
0
43
0
0
22
0
50
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
93
0
0
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
8
8
0
0
15
% N
% Pro:
15
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
22
0
8
15
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
43
0
0
0
0
0
50
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
8
8
15
0
0
0
0
8
0
8
% S
% Thr:
0
0
0
0
86
15
0
79
8
0
0
72
0
0
0
% T
% Val:
8
0
8
0
0
8
0
0
86
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _