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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRPL12 All Species: 35.45
Human Site: T135 Identified Species: 60
UniProt: P52815 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52815 NP_002940.2 198 21348 T135 T H F T V R L T E A K P V D K
Chimpanzee Pan troglodytes XP_001163363 198 21340 T135 T H F T V R L T E A K P V D K
Rhesus Macaque Macaca mulatta XP_001111712 198 21457 T135 T H F T V R L T E A N P V D K
Dog Lupus familis XP_850016 198 21413 T135 T H F T V R L T E A K P V D K
Cat Felis silvestris
Mouse Mus musculus Q9DB15 201 21690 T138 T H F T V R L T E A K P V D K
Rat Rattus norvegicus NP_001025071 276 29423 T213 T H F T V R L T E A K P V D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518289 336 34888 E282 S T S S T A N E A E S G L G G
Chicken Gallus gallus XP_001232214 194 20934 T131 T H F S V R L T E L K A T D K
Frog Xenopus laevis NP_001088496 190 20797 T127 T N F T V K L T E V N A T D K
Zebra Danio Brachydanio rerio NP_001017696 194 21202 T131 T H F T I K L T E F K A A D K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524742 182 19639 V119 T S F K V K L V K F D E K Q K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_499360 173 18420 T110 M T F T V K L T K F D D T K K
Sea Urchin Strong. purpuratus XP_790377 212 23073 N149 T Q F T V K L N K F D D T S K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53163 194 20631 D132 T V F T V K L D S F D T K T K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 95.9 87.8 N.A. 85.5 63 N.A. 25 61.1 60.6 57 N.A. 35.3 N.A. 37.8 44.3
Protein Similarity: 100 99.4 97.9 90.4 N.A. 90.5 66.3 N.A. 33.3 71.2 73.2 70.7 N.A. 52.5 N.A. 56.5 54.2
P-Site Identity: 100 100 93.3 100 N.A. 100 100 N.A. 0 73.3 60 66.6 N.A. 33.3 N.A. 40 40
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. 20 80 73.3 80 N.A. 46.6 N.A. 53.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 52.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 40 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 8 43 0 22 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 0 29 15 0 65 0 % D
% Glu: 0 0 0 0 0 0 0 8 65 8 0 8 0 0 0 % E
% Phe: 0 0 93 0 0 0 0 0 0 36 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 8 % G
% His: 0 58 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 8 0 43 0 0 22 0 50 0 15 8 93 % K
% Leu: 0 0 0 0 0 0 93 0 0 8 0 0 8 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 8 8 0 0 15 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 43 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 8 8 15 0 0 0 0 8 0 8 0 0 8 0 % S
% Thr: 86 15 0 79 8 0 0 72 0 0 0 8 29 8 0 % T
% Val: 0 8 0 0 86 0 0 8 0 8 0 0 43 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _