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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRPL12 All Species: 41.82
Human Site: Y60 Identified Species: 70.77
UniProt: P52815 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52815 NP_002940.2 198 21348 Y60 L D N A P K E Y P P K I Q Q L
Chimpanzee Pan troglodytes XP_001163363 198 21340 Y60 L D N A P K E Y P P K I Q Q L
Rhesus Macaque Macaca mulatta XP_001111712 198 21457 Y60 L D N A P K E Y P P K I Q Q L
Dog Lupus familis XP_850016 198 21413 Y60 L D N A P K E Y P P K I Q Q L
Cat Felis silvestris
Mouse Mus musculus Q9DB15 201 21690 Y61 L D N A P K E Y P P K I Q Q L
Rat Rattus norvegicus NP_001025071 276 29423 Y136 L D N A P K E Y P P K I Q Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518289 336 34888 Y162 L D D A P K D Y P P K I R R L
Chicken Gallus gallus XP_001232214 194 20934 Y58 L D T A A K E Y S P K V R Q L
Frog Xenopus laevis NP_001088496 190 20797 Y53 L D N A P K D Y P P K I H Q L
Zebra Danio Brachydanio rerio NP_001017696 194 21202 Y58 L D G T P K E Y S P K I Q Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524742 182 19639 P48 P E G A A K P P N P K L D S I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_499360 173 18420 I42 L P S E D R A I S A K V S S L
Sea Urchin Strong. purpuratus XP_790377 212 23073 Y76 R D N E P K Q Y P E K I S S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53163 194 20631 V50 H K D D V R P V D P K I S K I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 95.9 87.8 N.A. 85.5 63 N.A. 25 61.1 60.6 57 N.A. 35.3 N.A. 37.8 44.3
Protein Similarity: 100 99.4 97.9 90.4 N.A. 90.5 66.3 N.A. 33.3 71.2 73.2 70.7 N.A. 52.5 N.A. 56.5 54.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 73.3 66.6 86.6 80 N.A. 26.6 N.A. 20 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 80 93.3 80 N.A. 46.6 N.A. 40 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 52.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 72 15 0 8 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 79 15 8 8 0 15 0 8 0 0 0 8 0 0 % D
% Glu: 0 8 0 15 0 0 58 0 0 8 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 0 8 0 0 0 79 0 0 15 % I
% Lys: 0 8 0 0 0 86 0 0 0 0 100 0 0 8 0 % K
% Leu: 79 0 0 0 0 0 0 0 0 0 0 8 0 0 86 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 58 0 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 8 8 0 0 72 0 15 8 65 86 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 50 65 0 % Q
% Arg: 8 0 0 0 0 15 0 0 0 0 0 0 15 8 0 % R
% Ser: 0 0 8 0 0 0 0 0 22 0 0 0 22 22 0 % S
% Thr: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 8 0 0 8 0 0 0 15 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 79 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _