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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKQ
All Species:
7.88
Human Site:
S371
Identified Species:
13.33
UniProt:
P52824
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52824
NP_001338.2
942
101155
S371
K
A
G
S
A
V
I
S
E
E
G
R
S
P
G
Chimpanzee
Pan troglodytes
XP_517054
558
59289
S17
R
A
W
L
G
G
G
S
P
R
P
G
S
P
A
Rhesus Macaque
Macaca mulatta
XP_001085047
955
102930
S385
K
A
G
S
A
V
I
S
E
E
G
R
S
P
G
Dog
Lupus familis
XP_545985
883
96080
R312
S
G
A
R
G
R
P
R
G
S
G
A
A
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5E8
934
102236
E364
K
A
G
T
T
E
E
E
A
S
K
G
S
C
P
Rat
Rattus norvegicus
P49620
788
88503
G246
L
E
E
W
V
S
G
G
M
T
T
I
P
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514085
793
88823
I252
K
D
H
E
V
I
K
I
Y
P
G
W
L
K
I
Chicken
Gallus gallus
XP_424953
1170
127536
E615
I
N
R
N
D
A
A
E
D
S
N
L
G
S
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
S536
I
N
A
T
R
S
R
S
V
D
I
V
L
P
T
Honey Bee
Apis mellifera
XP_623068
890
99825
N302
E
T
E
L
C
D
P
N
P
V
L
N
L
N
R
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
R271
G
S
H
V
W
R
L
R
H
F
T
K
P
T
Y
Sea Urchin
Strong. purpuratus
XP_001203750
808
90577
R267
A
D
N
A
T
V
E
R
R
P
K
D
S
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169174
697
77246
S156
D
D
N
P
E
I
S
S
S
C
Y
Y
C
D
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
W187
F
L
G
G
S
P
I
W
C
C
L
W
C
Q
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.2
68.6
74.9
N.A.
80.6
24.3
N.A.
56.5
54.8
N.A.
N.A.
N.A.
20.1
40.8
25.6
34.9
Protein Similarity:
100
51.5
72.1
81.5
N.A.
86.4
39.9
N.A.
68.3
65.3
N.A.
N.A.
N.A.
32.7
58.8
41.5
52.6
P-Site Identity:
100
26.6
100
6.6
N.A.
26.6
0
N.A.
13.3
0
N.A.
N.A.
N.A.
13.3
0
0
13.3
P-Site Similarity:
100
33.3
100
13.3
N.A.
33.3
0
N.A.
20
13.3
N.A.
N.A.
N.A.
26.6
13.3
20
20
Percent
Protein Identity:
N.A.
28.6
N.A.
25.4
N.A.
N.A.
Protein Similarity:
N.A.
41.7
N.A.
39.9
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
29
15
8
15
8
8
0
8
0
0
8
8
0
8
% A
% Cys:
0
0
0
0
8
0
0
0
8
15
0
0
15
8
0
% C
% Asp:
8
22
0
0
8
8
0
0
8
8
0
8
0
8
0
% D
% Glu:
8
8
15
8
8
8
15
15
15
15
0
0
0
15
15
% E
% Phe:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
8
29
8
15
8
15
8
8
0
29
15
8
0
15
% G
% His:
0
0
15
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
15
0
0
0
0
15
22
8
0
0
8
8
0
0
8
% I
% Lys:
29
0
0
0
0
0
8
0
0
0
15
8
0
8
0
% K
% Leu:
8
8
0
15
0
0
8
0
0
0
15
8
22
8
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
15
15
8
0
0
0
8
0
0
8
8
0
8
0
% N
% Pro:
0
0
0
8
0
8
15
0
15
15
8
0
15
29
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
8
0
8
8
8
15
8
22
8
8
0
15
0
0
15
% R
% Ser:
8
8
0
15
8
15
8
36
8
22
0
0
36
8
0
% S
% Thr:
0
8
0
15
15
0
0
0
0
8
15
0
0
8
15
% T
% Val:
0
0
0
8
15
22
0
0
8
8
0
8
0
0
8
% V
% Trp:
0
0
8
8
8
0
0
8
0
0
0
15
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
8
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _