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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKQ
All Species:
1.21
Human Site:
S440
Identified Species:
2.05
UniProt:
P52824
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52824
NP_001338.2
942
101155
S440
L
L
G
R
Q
A
E
S
P
E
S
F
Q
L
V
Chimpanzee
Pan troglodytes
XP_517054
558
59289
W82
H
L
C
S
D
F
I
W
G
L
A
G
F
L
C
Rhesus Macaque
Macaca mulatta
XP_001085047
955
102930
G454
L
L
G
R
Q
A
E
G
P
E
S
F
Q
L
V
Dog
Lupus familis
XP_545985
883
96080
G381
L
L
G
R
Q
A
E
G
P
E
G
F
Q
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5E8
934
102236
D432
L
F
G
Q
Q
V
E
D
K
E
R
F
Q
L
I
Rat
Rattus norvegicus
P49620
788
88503
V311
Y
A
V
H
Q
R
C
V
S
N
S
I
P
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514085
793
88823
L317
M
V
L
E
D
Q
E
L
I
L
G
R
L
K
A
Chicken
Gallus gallus
XP_424953
1170
127536
C684
L
L
G
R
Q
A
E
C
L
Q
N
F
R
L
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
K617
I
K
S
G
Q
R
M
K
C
S
A
C
Q
L
V
Honey Bee
Apis mellifera
XP_623068
890
99825
K370
K
F
G
L
Q
N
F
K
S
E
D
Y
R
C
S
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
N336
Y
H
H
W
Q
D
A
N
A
T
A
K
C
V
K
Sea Urchin
Strong. purpuratus
XP_001203750
808
90577
I332
S
Y
I
S
V
E
E
I
I
D
M
S
L
H
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169174
697
77246
Q221
Q
S
V
K
E
I
G
Q
G
S
G
I
S
G
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
T252
G
A
N
E
L
A
S
T
A
L
A
S
I
R
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.2
68.6
74.9
N.A.
80.6
24.3
N.A.
56.5
54.8
N.A.
N.A.
N.A.
20.1
40.8
25.6
34.9
Protein Similarity:
100
51.5
72.1
81.5
N.A.
86.4
39.9
N.A.
68.3
65.3
N.A.
N.A.
N.A.
32.7
58.8
41.5
52.6
P-Site Identity:
100
13.3
93.3
86.6
N.A.
53.3
13.3
N.A.
6.6
66.6
N.A.
N.A.
N.A.
26.6
20
6.6
6.6
P-Site Similarity:
100
20
93.3
86.6
N.A.
66.6
13.3
N.A.
20
86.6
N.A.
N.A.
N.A.
40
33.3
26.6
13.3
Percent
Protein Identity:
N.A.
28.6
N.A.
25.4
N.A.
N.A.
Protein Similarity:
N.A.
41.7
N.A.
39.9
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
36
8
0
15
0
29
0
0
0
8
% A
% Cys:
0
0
8
0
0
0
8
8
8
0
0
8
8
8
15
% C
% Asp:
0
0
0
0
15
8
0
8
0
8
8
0
0
0
0
% D
% Glu:
0
0
0
15
8
8
50
0
0
36
0
0
0
0
0
% E
% Phe:
0
15
0
0
0
8
8
0
0
0
0
36
8
0
0
% F
% Gly:
8
0
43
8
0
0
8
15
15
0
22
8
0
15
0
% G
% His:
8
8
8
8
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
0
8
0
0
8
8
8
15
0
0
15
8
0
15
% I
% Lys:
8
8
0
8
0
0
0
15
8
0
0
8
0
8
15
% K
% Leu:
36
36
8
8
8
0
0
8
8
22
0
0
15
50
0
% L
% Met:
8
0
0
0
0
0
8
0
0
0
8
0
0
0
8
% M
% Asn:
0
0
8
0
0
8
0
8
0
8
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
22
0
0
0
8
0
0
% P
% Gln:
8
0
0
8
65
8
0
8
0
8
0
0
36
0
0
% Q
% Arg:
0
0
0
29
0
15
0
0
0
0
8
8
15
8
0
% R
% Ser:
8
8
8
15
0
0
8
8
15
15
22
15
8
0
8
% S
% Thr:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% T
% Val:
0
8
15
0
8
8
0
8
0
0
0
0
0
8
36
% V
% Trp:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
15
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _