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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKQ
All Species:
9.7
Human Site:
S517
Identified Species:
16.41
UniProt:
P52824
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52824
NP_001338.2
942
101155
S517
L
S
P
E
E
Y
S
S
L
L
H
E
A
G
A
Chimpanzee
Pan troglodytes
XP_517054
558
59289
G154
A
W
A
G
G
K
A
G
S
A
V
I
S
E
E
Rhesus Macaque
Macaca mulatta
XP_001085047
955
102930
S531
L
S
P
E
E
Y
S
S
L
L
H
E
A
V
A
Dog
Lupus familis
XP_545985
883
96080
S458
L
S
T
Q
E
Y
A
S
L
L
D
E
A
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5E8
934
102236
N509
L
S
P
Q
D
Y
S
N
L
L
H
E
A
M
A
Rat
Rattus norvegicus
P49620
788
88503
G383
L
S
T
A
C
D
G
G
E
L
K
D
H
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514085
793
88823
A389
S
V
S
H
V
Y
S
A
Q
G
A
V
V
L
H
Chicken
Gallus gallus
XP_424953
1170
127536
N761
L
S
P
E
E
Y
M
N
I
L
K
D
E
L
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
S693
V
Q
S
K
L
F
G
S
K
E
I
V
A
L
A
Honey Bee
Apis mellifera
XP_623068
890
99825
N447
L
S
E
R
S
Y
E
N
M
L
T
E
F
L
G
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
F408
T
S
L
K
N
H
N
F
S
S
H
S
A
S
L
Sea Urchin
Strong. purpuratus
XP_001203750
808
90577
Q404
K
D
K
C
A
C
H
Q
G
A
Q
M
F
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169174
697
77246
P293
G
K
Y
A
L
A
K
P
L
S
Q
H
S
V
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
L324
D
S
D
S
N
G
K
L
E
K
K
P
S
V
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.2
68.6
74.9
N.A.
80.6
24.3
N.A.
56.5
54.8
N.A.
N.A.
N.A.
20.1
40.8
25.6
34.9
Protein Similarity:
100
51.5
72.1
81.5
N.A.
86.4
39.9
N.A.
68.3
65.3
N.A.
N.A.
N.A.
32.7
58.8
41.5
52.6
P-Site Identity:
100
0
93.3
66.6
N.A.
73.3
20
N.A.
13.3
53.3
N.A.
N.A.
N.A.
20
33.3
20
0
P-Site Similarity:
100
13.3
93.3
80
N.A.
93.3
26.6
N.A.
20
73.3
N.A.
N.A.
N.A.
40
46.6
40
0
Percent
Protein Identity:
N.A.
28.6
N.A.
25.4
N.A.
N.A.
Protein Similarity:
N.A.
41.7
N.A.
39.9
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
15
8
8
15
8
0
15
8
0
43
0
43
% A
% Cys:
0
0
0
8
8
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
0
8
8
0
0
0
0
8
15
0
0
0
% D
% Glu:
0
0
8
22
29
0
8
0
15
8
0
36
8
8
8
% E
% Phe:
0
0
0
0
0
8
0
8
0
0
0
0
15
0
0
% F
% Gly:
8
0
0
8
8
8
15
15
8
8
0
0
0
8
15
% G
% His:
0
0
0
8
0
8
8
0
0
0
29
8
8
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
8
8
0
8
0
% I
% Lys:
8
8
8
15
0
8
15
0
8
8
22
0
0
0
15
% K
% Leu:
50
0
8
0
15
0
0
8
36
50
0
0
0
29
15
% L
% Met:
0
0
0
0
0
0
8
0
8
0
0
8
0
8
0
% M
% Asn:
0
0
0
0
15
0
8
22
0
0
0
0
0
0
0
% N
% Pro:
0
0
29
0
0
0
0
8
0
0
0
8
0
0
0
% P
% Gln:
0
8
0
15
0
0
0
8
8
0
15
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
65
15
8
8
0
29
29
15
15
0
8
22
8
0
% S
% Thr:
8
0
15
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
8
8
0
0
8
0
0
0
0
0
8
15
8
36
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
50
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _