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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKQ
All Species:
19.7
Human Site:
S699
Identified Species:
33.33
UniProt:
P52824
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52824
NP_001338.2
942
101155
S699
Y
S
G
E
D
P
F
S
V
L
L
S
V
D
E
Chimpanzee
Pan troglodytes
XP_517054
558
59289
A332
D
S
S
C
M
A
Q
A
G
V
V
C
S
H
A
Rhesus Macaque
Macaca mulatta
XP_001085047
955
102930
S713
Y
S
G
E
D
P
L
S
V
L
L
S
V
D
E
Dog
Lupus familis
XP_545985
883
96080
S640
Y
S
G
E
D
P
L
S
V
L
V
S
V
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5E8
934
102236
S691
Y
S
G
E
D
P
F
S
V
L
V
S
V
D
E
Rat
Rattus norvegicus
P49620
788
88503
P561
R
W
Y
L
E
V
M
P
R
E
E
V
E
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514085
793
88823
T567
D
V
L
M
D
R
W
T
I
L
L
D
A
Q
E
Chicken
Gallus gallus
XP_424953
1170
127536
S943
Y
S
G
E
D
P
Y
S
I
L
I
S
V
D
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
K922
Y
T
D
E
P
I
G
K
I
L
R
E
I
G
M
Honey Bee
Apis mellifera
XP_623068
890
99825
L629
Y
T
G
D
E
D
P
L
N
L
L
R
D
V
I
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
G586
I
N
N
Y
F
S
I
G
V
D
A
S
I
A
H
Sea Urchin
Strong. purpuratus
XP_001203750
808
90577
I582
C
S
S
P
A
I
A
I
L
P
L
G
T
G
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169174
697
77246
K471
G
T
E
G
E
C
T
K
Q
I
K
F
M
T
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
L502
L
N
Q
Q
G
K
Q
L
Q
P
P
K
Y
M
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.2
68.6
74.9
N.A.
80.6
24.3
N.A.
56.5
54.8
N.A.
N.A.
N.A.
20.1
40.8
25.6
34.9
Protein Similarity:
100
51.5
72.1
81.5
N.A.
86.4
39.9
N.A.
68.3
65.3
N.A.
N.A.
N.A.
32.7
58.8
41.5
52.6
P-Site Identity:
100
6.6
93.3
86.6
N.A.
93.3
0
N.A.
26.6
80
N.A.
N.A.
N.A.
20
26.6
13.3
13.3
P-Site Similarity:
100
26.6
93.3
93.3
N.A.
100
13.3
N.A.
46.6
100
N.A.
N.A.
N.A.
40
46.6
26.6
20
Percent
Protein Identity:
N.A.
28.6
N.A.
25.4
N.A.
N.A.
Protein Similarity:
N.A.
41.7
N.A.
39.9
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
8
8
0
0
8
0
8
8
8
% A
% Cys:
8
0
0
8
0
8
0
0
0
0
0
8
0
0
0
% C
% Asp:
15
0
8
8
43
8
0
0
0
8
0
8
8
36
0
% D
% Glu:
0
0
8
43
22
0
0
0
0
8
8
8
8
0
43
% E
% Phe:
0
0
0
0
8
0
15
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
43
8
8
0
8
8
8
0
0
8
0
15
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% H
% Ile:
8
0
0
0
0
15
8
8
22
8
8
0
15
0
8
% I
% Lys:
0
0
0
0
0
8
0
15
0
0
8
8
0
0
0
% K
% Leu:
8
0
8
8
0
0
15
15
8
58
36
0
0
0
0
% L
% Met:
0
0
0
8
8
0
8
0
0
0
0
0
8
8
8
% M
% Asn:
0
15
8
0
0
0
0
0
8
0
0
0
0
8
22
% N
% Pro:
0
0
0
8
8
36
8
8
0
15
8
0
0
0
0
% P
% Gln:
0
0
8
8
0
0
15
0
15
0
0
0
0
8
0
% Q
% Arg:
8
0
0
0
0
8
0
0
8
0
8
8
0
0
0
% R
% Ser:
0
50
15
0
0
8
0
36
0
0
0
43
8
0
0
% S
% Thr:
0
22
0
0
0
0
8
8
0
0
0
0
8
8
0
% T
% Val:
0
8
0
0
0
8
0
0
36
8
22
8
36
8
0
% V
% Trp:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
50
0
8
8
0
0
8
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _