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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAPZA1 All Species: 47.27
Human Site: S106 Identified Species: 65
UniProt: P52907 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52907 NP_006126.1 286 32923 S106 D H L R K E A S D P Q P E E A
Chimpanzee Pan troglodytes XP_513632 286 32891 S106 D H L R K E A S D P Q P E E A
Rhesus Macaque Macaca mulatta XP_001107677 286 32932 S106 D H L R K E A S D P Q P E E V
Dog Lupus familis XP_533066 286 32966 S106 D H L R K E A S D P Q P E D V
Cat Felis silvestris
Mouse Mus musculus P47753 286 32921 S106 D H L R K E A S D P Q P E D V
Rat Rattus norvegicus B2GUZ5 286 32891 S106 D H L R K E A S D P Q P E D V
Wallaby Macropus eugenll A4D7S9 286 32928 T106 D H L R K E A T D P R P C E G
Platypus Ornith. anatinus Q07E00 286 32980 T106 D H L R K E A T D P R P Q E P
Chicken Gallus gallus P13127 286 32941 S106 D H L R K E A S D P Q P E D T
Frog Xenopus laevis P25229 256 29408 P78 L R K E A S D P H P D D S D V
Zebra Danio Brachydanio rerio XP_689117 286 32709 S106 D H L R K E A S D P Q P Y E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W2N0 286 32741 S104 D H L R K E A S D Y Q D V E A
Honey Bee Apis mellifera XP_624862 288 32841 Y108 L R K E A Q D Y E P Y E P D S
Nematode Worm Caenorhab. elegans P34685 282 32163 L104 V R K E A A D L Q P H P A E S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82631 308 35020 T111 D H V K Q I C T K V R P A N D
Baker's Yeast Sacchar. cerevisiae P28495 268 30681 V86 V N S V I F S V N H L E R K G
Red Bread Mold Neurospora crassa Q9P5K9 269 29610 Y85 E S S S S F A Y D H I T Q K A
Conservation
Percent
Protein Identity: 100 96.8 99.6 97.1 N.A. 96.5 97.1 86 84.9 92.3 78.6 81.4 N.A. 63.2 64.2 55.5 N.A.
Protein Similarity: 100 97.1 99.6 98.9 N.A. 98.9 99.3 94 94 96.1 85.3 90.9 N.A. 76.2 77.7 69.5 N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 86.6 73.3 73.3 86.6 6.6 86.6 N.A. 80 6.6 20 N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 93.3 86.6 93.3 93.3 13.3 86.6 N.A. 80 33.3 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 28.9 32.1 35.6
Protein Similarity: N.A. N.A. N.A. 50 52.4 58
P-Site Identity: N.A. N.A. N.A. 20 0 20
P-Site Similarity: N.A. N.A. N.A. 53.3 26.6 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 18 6 71 0 0 0 0 0 12 0 24 % A
% Cys: 0 0 0 0 0 0 6 0 0 0 0 0 6 0 0 % C
% Asp: 71 0 0 0 0 0 18 0 71 0 6 12 0 36 6 % D
% Glu: 6 0 0 18 0 65 0 0 6 0 0 12 42 48 0 % E
% Phe: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18 % G
% His: 0 71 0 0 0 0 0 0 6 12 6 0 0 0 0 % H
% Ile: 0 0 0 0 6 6 0 0 0 0 6 0 0 0 0 % I
% Lys: 0 0 18 6 65 0 0 0 6 0 0 0 0 12 0 % K
% Leu: 12 0 65 0 0 0 0 6 0 0 6 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 6 0 0 0 0 0 0 6 0 0 0 0 6 0 % N
% Pro: 0 0 0 0 0 0 0 6 0 77 0 71 6 0 6 % P
% Gln: 0 0 0 0 6 6 0 0 6 0 53 0 12 0 0 % Q
% Arg: 0 18 0 65 0 0 0 0 0 0 18 0 6 0 0 % R
% Ser: 0 6 12 6 6 6 6 53 0 0 0 0 6 0 12 % S
% Thr: 0 0 0 0 0 0 0 18 0 0 0 6 0 0 6 % T
% Val: 12 0 6 6 0 0 0 6 0 6 0 0 6 0 30 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 12 0 6 6 0 6 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _