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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAPZA1 All Species: 30
Human Site: S123 Identified Species: 41.25
UniProt: P52907 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52907 NP_006126.1 286 32923 S123 G L K S W R E S C D S A L R A
Chimpanzee Pan troglodytes XP_513632 286 32891 S123 G L K S W R E S C D S A L R A
Rhesus Macaque Macaca mulatta XP_001107677 286 32932 S123 G L K S W R E S C D S A L R A
Dog Lupus familis XP_533066 286 32966 S123 G L K S W R E S C D N A L R A
Cat Felis silvestris
Mouse Mus musculus P47753 286 32921 S123 G L K S W R E S C D S A L R A
Rat Rattus norvegicus B2GUZ5 286 32891 S123 G L K S W R D S C D S A L R A
Wallaby Macropus eugenll A4D7S9 286 32928 S123 A I E S W R H S V E T A M R A
Platypus Ornith. anatinus Q07E00 286 32980 S123 A V E S W R H S V E T A M R A
Chicken Gallus gallus P13127 286 32941 A123 A L K Q W R D A C D S A L R A
Frog Xenopus laevis P25229 256 29408 D95 K S W R D A C D L A L R A Y V
Zebra Danio Brachydanio rerio XP_689117 286 32709 A123 A L R S W R D A C D D A L S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W2N0 286 32741 A121 T A E P W R A A L D L E T L A
Honey Bee Apis mellifera XP_624862 288 32841 Q125 E P W R S A L Q D E I T T Y T
Nematode Worm Caenorhab. elegans P34685 282 32163 L121 T E Q W R Q A L Q T Q L D I Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82631 308 35020 E128 L P S L Y I E E Y R Y A L D A
Baker's Yeast Sacchar. cerevisiae P28495 268 30681 H103 I E P Y E F T H A K I E K G Q
Red Bread Mold Neurospora crassa Q9P5K9 269 29610 G102 V Q S H V L E G E Q T D L V K
Conservation
Percent
Protein Identity: 100 96.8 99.6 97.1 N.A. 96.5 97.1 86 84.9 92.3 78.6 81.4 N.A. 63.2 64.2 55.5 N.A.
Protein Similarity: 100 97.1 99.6 98.9 N.A. 98.9 99.3 94 94 96.1 85.3 90.9 N.A. 76.2 77.7 69.5 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 100 93.3 46.6 46.6 73.3 0 60 N.A. 26.6 0 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 80 80 86.6 0 80 N.A. 40 6.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 28.9 32.1 35.6
Protein Similarity: N.A. N.A. N.A. 50 52.4 58
P-Site Identity: N.A. N.A. N.A. 26.6 0 13.3
P-Site Similarity: N.A. N.A. N.A. 33.3 0 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 6 0 0 0 12 12 18 6 6 0 65 6 0 71 % A
% Cys: 0 0 0 0 0 0 6 0 48 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 6 0 18 6 6 53 6 6 6 6 0 % D
% Glu: 6 12 18 0 6 0 42 6 6 18 0 12 0 0 0 % E
% Phe: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % F
% Gly: 36 0 0 0 0 0 0 6 0 0 0 0 0 6 0 % G
% His: 0 0 0 6 0 0 12 6 0 0 0 0 0 0 0 % H
% Ile: 6 6 0 0 0 6 0 0 0 0 12 0 0 6 0 % I
% Lys: 6 0 42 0 0 0 0 0 0 6 0 0 6 0 6 % K
% Leu: 6 48 0 6 0 6 6 6 12 0 12 6 59 6 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % N
% Pro: 0 12 6 6 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 6 6 6 0 6 0 6 6 6 6 0 0 0 6 % Q
% Arg: 0 0 6 12 6 65 0 0 0 6 0 6 0 53 0 % R
% Ser: 0 6 12 53 6 0 0 48 0 0 36 0 0 6 0 % S
% Thr: 12 0 0 0 0 0 6 0 0 6 18 6 12 0 6 % T
% Val: 6 6 0 0 6 0 0 0 12 0 0 0 0 6 6 % V
% Trp: 0 0 12 6 65 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 6 6 0 0 0 6 0 6 0 0 12 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _