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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAPZA1 All Species: 44.55
Human Site: S215 Identified Species: 61.25
UniProt: P52907 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52907 NP_006126.1 286 32923 S215 S H K D V Q D S L T V S N E A
Chimpanzee Pan troglodytes XP_513632 286 32891 S215 S H K D V Q D S L T V S N E A
Rhesus Macaque Macaca mulatta XP_001107677 286 32932 S215 S H K D V Q D S L T V S N E A
Dog Lupus familis XP_533066 286 32966 S215 S H K D V Q D S V T V S N E V
Cat Felis silvestris
Mouse Mus musculus P47753 286 32921 S215 S H K D V Q D S V T V S N E V
Rat Rattus norvegicus B2GUZ5 286 32891 S215 S H K D V Q D S V T V S N E V
Wallaby Macropus eugenll A4D7S9 286 32928 S215 S H K D I Q E S L T V S N E V
Platypus Ornith. anatinus Q07E00 286 32980 S215 S H K D I Q D S L T V S N E V
Chicken Gallus gallus P13127 286 32941 S215 S H K D I Q D S V Q V S S D V
Frog Xenopus laevis P25229 256 29408 T187 K D V Q E S I T I S G E A Q T
Zebra Danio Brachydanio rerio XP_689117 286 32709 S215 S H K E V E E S I V V T N E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W2N0 286 32741 R213 L V S S K E C R E S V V V S N
Honey Bee Apis mellifera XP_624862 288 32841 S217 S S K E V K E S L P I S S E K
Nematode Worm Caenorhab. elegans P34685 282 32163 V213 E K E P V L K V N V S A D F D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82631 308 35020 N220 A H Y F E E G N V E L D A K K
Baker's Yeast Sacchar. cerevisiae P28495 268 30681 Q195 E D G N V S F Q S G K D I N Q
Red Bread Mold Neurospora crassa Q9P5K9 269 29610 T194 V R L L T N K T V T A T V S S
Conservation
Percent
Protein Identity: 100 96.8 99.6 97.1 N.A. 96.5 97.1 86 84.9 92.3 78.6 81.4 N.A. 63.2 64.2 55.5 N.A.
Protein Similarity: 100 97.1 99.6 98.9 N.A. 98.9 99.3 94 94 96.1 85.3 90.9 N.A. 76.2 77.7 69.5 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 86.6 86.6 80 86.6 60 0 53.3 N.A. 6.6 46.6 6.6 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 93.3 93.3 86.6 26.6 86.6 N.A. 20 80 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 28.9 32.1 35.6
Protein Similarity: N.A. N.A. N.A. 50 52.4 58
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 46.6 13.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 0 0 0 0 0 0 0 0 6 6 12 0 18 % A
% Cys: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 0 53 0 0 48 0 0 0 0 12 6 6 6 % D
% Glu: 12 0 6 12 12 18 18 0 6 6 0 6 0 59 0 % E
% Phe: 0 0 0 6 0 0 6 0 0 0 0 0 0 6 0 % F
% Gly: 0 0 6 0 0 0 6 0 0 6 6 0 0 0 0 % G
% His: 0 65 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 18 0 6 0 12 0 6 0 6 0 0 % I
% Lys: 6 6 65 0 6 6 12 0 0 0 6 0 0 6 12 % K
% Leu: 6 0 6 6 0 6 0 0 36 0 6 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 6 0 6 0 6 6 0 0 0 53 6 6 % N
% Pro: 0 0 0 6 0 0 0 0 0 6 0 0 0 0 0 % P
% Gln: 0 0 0 6 0 53 0 6 0 6 0 0 0 6 6 % Q
% Arg: 0 6 0 0 0 0 0 6 0 0 0 0 0 0 0 % R
% Ser: 65 6 6 6 0 12 0 65 6 12 6 59 12 12 6 % S
% Thr: 0 0 0 0 6 0 0 12 0 53 0 12 0 0 6 % T
% Val: 6 6 6 0 59 0 0 6 36 12 65 6 12 0 42 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _