KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPZA1
All Species:
56.36
Human Site:
S251
Identified Species:
77.5
UniProt:
P52907
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52907
NP_006126.1
286
32923
S251
S
E
N
Y
Q
T
M
S
D
T
T
F
K
A
L
Chimpanzee
Pan troglodytes
XP_513632
286
32891
S251
S
E
N
Y
Q
T
M
S
D
T
T
F
K
A
L
Rhesus Macaque
Macaca mulatta
XP_001107677
286
32932
S251
S
E
N
Y
Q
T
M
S
D
T
T
F
K
A
L
Dog
Lupus familis
XP_533066
286
32966
S251
S
E
N
Y
Q
T
M
S
D
T
T
F
K
A
L
Cat
Felis silvestris
Mouse
Mus musculus
P47753
286
32921
S251
S
E
N
Y
Q
T
M
S
D
T
T
F
K
A
L
Rat
Rattus norvegicus
B2GUZ5
286
32891
S251
S
E
N
Y
Q
T
M
S
D
T
T
F
K
A
L
Wallaby
Macropus eugenll
A4D7S9
286
32928
S251
S
E
N
Y
Q
T
M
S
D
T
T
F
K
A
L
Platypus
Ornith. anatinus
Q07E00
286
32980
S251
N
E
N
Y
Q
T
M
S
D
T
T
F
K
A
L
Chicken
Gallus gallus
P13127
286
32941
S251
S
E
N
Y
Q
T
M
S
D
T
T
F
K
A
L
Frog
Xenopus laevis
P25229
256
29408
T223
N
Y
Q
T
M
S
D
T
T
F
K
A
L
R
R
Zebra Danio
Brachydanio rerio
XP_689117
286
32709
S251
S
E
N
Y
Q
T
M
S
D
T
T
F
K
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W2N0
286
32741
T249
A
I
S
E
N
Y
Q
T
M
S
D
T
T
F
K
Honey Bee
Apis mellifera
XP_624862
288
32841
S253
S
E
N
Y
Q
T
M
S
D
T
T
F
K
A
L
Nematode Worm
Caenorhab. elegans
P34685
282
32163
S249
Q
E
N
Y
A
N
M
S
D
T
T
F
K
A
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82631
308
35020
Y256
I
R
H
H
E
T
E
Y
L
A
S
L
E
V
A
Baker's Yeast
Sacchar. cerevisiae
P28495
268
30681
N231
D
L
S
F
F
D
L
N
E
K
Q
F
K
A
L
Red Bread Mold
Neurospora crassa
Q9P5K9
269
29610
S230
N
K
S
F
T
S
L
S
E
G
A
F
K
G
L
Conservation
Percent
Protein Identity:
100
96.8
99.6
97.1
N.A.
96.5
97.1
86
84.9
92.3
78.6
81.4
N.A.
63.2
64.2
55.5
N.A.
Protein Similarity:
100
97.1
99.6
98.9
N.A.
98.9
99.3
94
94
96.1
85.3
90.9
N.A.
76.2
77.7
69.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
100
93.3
100
0
100
N.A.
0
100
80
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
100
100
100
20
100
N.A.
26.6
100
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.9
32.1
35.6
Protein Similarity:
N.A.
N.A.
N.A.
50
52.4
58
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
40
60
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
6
0
0
0
0
6
6
6
0
77
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
0
0
0
6
6
0
71
0
6
0
0
0
0
% D
% Glu:
0
71
0
6
6
0
6
0
12
0
0
0
6
0
0
% E
% Phe:
0
0
0
12
6
0
0
0
0
6
0
83
0
6
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
6
0
0
0
6
0
% G
% His:
0
0
6
6
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
6
0
0
0
0
0
0
0
6
6
0
83
0
6
% K
% Leu:
0
6
0
0
0
0
12
0
6
0
0
6
6
0
83
% L
% Met:
0
0
0
0
6
0
71
0
6
0
0
0
0
0
0
% M
% Asn:
18
0
71
0
6
6
0
6
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
6
0
6
0
65
0
6
0
0
0
6
0
0
0
0
% Q
% Arg:
0
6
0
0
0
0
0
0
0
0
0
0
0
6
6
% R
% Ser:
59
0
18
0
0
12
0
77
0
6
6
0
0
0
0
% S
% Thr:
0
0
0
6
6
71
0
12
6
71
71
6
6
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
0
71
0
6
0
6
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _